FERGU pathology Flashcards
Abdominal CT
mass in the right kidney
Kidney section
well-circumscribed yellow mass with cystic and hemorrhagic degeneration
Renal cell carcinoma
Renal cell carcinoma
clear cell type
tumour cells with cytoplasmic lipid and glycogen
vascularized
bladder mucosa
Non-invasive papillary transitional cell carcinoma, low grade
correlates with exophytic papillary mass
transitional cell carcinoma in-situ
flat type (cytologically high grade)
correlates with mucosal erythema
Large ulcerated transitional cell carcinoma of the bladder
invasion through bladder wall
transitional cell carcinoma of the bladder
Invasive, high-grade (3/3) transitional cell carcinoma involving the muscularis propria
Stage T2
5 yr survival 25-50%
transitional cell carcinoma of the bladder
Invasive TCC involving peri-visceral fat
Stage T3
15% 5-yr survival
Dilated renal pelvi-calyceal system
thinned renal parenchyma with mottled discolouration of the cut surface
kidney stone in renal pelvis
Hydronephrosis secondary to nephrolithiasis
Kidney
edema, congestion
acute inflammation with pus in the collecting system
kidney
acute inflammation
tubular atrophy
calcification
benign reactive renal pelvic urothelium
renal cortex
Renal cortical atrophy with shrunken and obsolete glomeruli
Tubular atrophy, interstitial chronic inflammation
specimen from TUPR
Hyperplastic nodule with glandular and stromal elements
circumscribed
compact with benign cells
BPH
BPH
compression of urethra
thickening of bladder wall
BPH
prostatic needle core biopsy
benign
well-formed orderly glands with contours
bland cytological features and a basal layer
prostatic needle biopsy
both cores positive for prostatic adenocarcinoma
crowded malignant microacini infiltration in between and around larger benign glands
malignant microacini lined by atypical cells with nucleomegaly, hyperchromaticity and prominent nucleoli
no basal layer
prostectomy
no external evidence of tumour
a large tumour with irregular yellow nodules involving the peripheral and transition zone
carcinoma likely originated from the peripheral zone, then grow to involve the transition zone
appears yellow due to high cytoplasmic fat content
Circumscribed large mass replaceing most of testis
solid, lobulated, tan cut surface
testis
seminoma
sheets of relatively evenly-spaced tumour cells with variably cleared cytoplasm
(cleared because it is glycogen-rich)
distinct cell boundaries
tumour cells have large, oval nuclei with one or two prominent nucleoli
tumour is transected by fibrous bands with scattered lymphocytes
occasional poorly-formed granuloma present
no necrosis or hemorrhage
testis
seminoma
sheets of relatively evenly-spaced tumour cells with variably cleared cytoplasm
(cleared because it is glycogen-rich)
distinct cell boundaries tumour cells have large, oval nuclei with one or two prominent nucleoli
tumour is transected by fibrous bands with scattered lymphocytes
occasional poorly-formed granuloma present
no necrosis or hemorrhage
TB of th epididymis with extension in to the testis
TB of the epididymis with extension into testis
