Female Reproductive System Flashcards
5 organs of the female reproductive system
Ovaries, uterine tubes, uterus, vagina and breasts
What type of epithelium covers the ovaries
What is the tunica albuginea
Simple squamous or cubodial
DCT layer under the epithelium
What are located in the superficial surface of the ovary (cortex)
Primordial follicles
Layers of the ovary from superficial to deep
What layer contains the follicles
Epithelium, tunica albuginea, cortex, medulla
In the stroma of the cortex
What is the stroma composed of
Function of stroma
Connective tissue with spindle shaped fibroblasts
Respond to hormonal stimuli
What is the medulla composed of
Loose connective tissue with a rich vascular bed
Name 3 parts of ovarian follicle from innermost to outermost
Zona pellucida, granulosa cells, and theca cells
Basal lamina marks boundary between
Where is it located
The follicle and surrounding stroma
It underlies the follicular cells
Primordial follicles:
- Where are they located
- What do they consist of
- Superficial layer of the cortical region
2. An oocyte surrounded by a single layer of flattened follicular cells
Difference in structure of primordial and secondary follicles
Secondary follicles have an antrum
- When primordial follicle undergoes mitosis, what do they form
- What is it then called
- As they continue to proliferate what do they form next and what type of epithelium?
- Single layer of cuboidal cells
- Unilaminar primary follicle
- Granulosa layer; Stratified follicular epithelium- zona pellucida is also formed
Secondary/antral follicle
- What are cumulus oophorus cells
- What do these cells contain
- Cells that protrude towards the interior of the antrum
2. The oocyte and group of follicular cells around the oocyte (corona radiata)
Stromal cells differentiate into (3 differentiations)
Theca folliculi-> theca interna -> theca externa
Theca interna consists of ?
What do they synthesize; what does this get converted into
Steroid secreting cells
Androstenedione; estrogen (under FSH influence)
All follicles except for one undergo atresia; when is atresia most intense?
At times of marked hormone change (after birth, puberty, during pregnancy)
Two menstrual cycles that happen simultaneously
Ovarian cycle and uterine cycle
Ovarian cycle
- Controlled by
- Target ovaries to
- GnRH, LH, and FSH
2. Secretion of estrogen and progesterone
Uterine cycle
- Estrogen and progesterone target?
- What does this cause?
- The endometrium of the uterus
2. Causes it to grow and secrete uterine milk into the uterine lumen
Ovarian cycle
- First phase is? What days?
- In this phase, FSH stimulates?
- LH stimulates
- Follicular cells secrete?
- What gets developed?
- Follicular phase; days 1-14
- Growth from primordial follicle to primary follicle
- Estrogen secretion from follicular cells
- Zona pellucida
- Antrum
Ovarian cycle-Ovulation
- Day?
- What does ovulation consist of
- Stimulus for ovulation?
- What is the fate of the follicular cells of the ruptured graffian follicle
- 14
- Rupture of wall of mature follicle and to release oocyte/corona radiata
- Surge of LH in response to high levels of estrogen
- Remain in the ovary and become corpus luteum
When is first meiotic division completed?
When does second mitotic division begin?
When does it stop?
Just prior to ovulation
Right after expulsion of first polar body;
Metaphase
Ovarian cycle- luteal phase
- Days?
- What happens in this phase
- LH levels increase or decrease
- 14-28
- Ruptured follicle transformation into corpus luteum; cells of corpus luteum produce estrogen/progesterone
- Decrease from LH surge