Female Reproductive System Flashcards

1
Q

What are the functions of the female reproductive system?

A

produces secondary oocytes and hormones

provides sites of fertilisation, implantation and development and the delivery of the foetus.

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2
Q

What are the functions of the uterus

A
  • Pathway for sperm to reach the fallopian tubes
  • To receive, retain, protect and nourish the fertilised ovum and developing embryo / fetus
  • To expel the mature foetus at the end of pregnancy
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3
Q

What is the structure and position of the uterus?

A
  • Hollow, muscular organ within the
    pelvis
  • Pear shaped.
  • Positioned anterior to the rectum
    and posterior to the bladder in non pregnant females
  • It lies mostly within the pelvis cavity
  • In non pregnant women it measures approximately 7.5cm in length and 5cm in diameter.
  • It is nearly 2.5cm thick.
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4
Q

What are the divisions of the uterus?

A

• Fundus – top part
• Body / corpus – central part
• Cervix – lower part projecting into the vagina

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5
Q

The body of the uterus is divided into 3 layers, what are they?

A
  • Endometrium – inner mucosal layer which undergoes the cyclic changes during the menstrual cycle and is shed during menstruation
  • Myometrium – the thick muscular middle layer responsible for uterine contractions
    during menstruation and childbirth
  • Serosa (perimetrium) – the outermost think peritoneal later covering the uterus
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6
Q

What is the position of the uterus?

A

It is held in place by ligaments – 2 of each
• Uterosacral ligaments from posterior cervix to sacrum
• Cardinal ligaments from side of cervix to ischial spines
• Pubocervical ligament
• From side of cervix to pubic symph

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7
Q

Whet is the blood supply to the uterus?

A
  • Arterial blood passes into the internal iliac artery and then into the uterine arteries.
  • The uterus has an extensive blood supply which is essential to support regrowth of the endometrium and implantation of the ovum and development of the placenta.
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8
Q

What are the functions of the cervix

A

Acts as a mechanical barrier
to infectious microorganisms
present in the vagina
The external os is a very small
opening with thick sticky
mucous – plug
During ovulation, the plug
becomes watery to facilitate
sperm travel under the
influence of oestrogen

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9
Q

What is the cervix

A

This is the lower part of the
uterus situated between the
external os and the internal os
* The cervical canal connects
the interior of the vagina and
the cavity of the body of the
uterus
* It is 2-3cm in length
* Width depends on age – widest in premenopausal
women at 8mm

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10
Q

what does the cervical canal contain

A

It dips into the vagina forming the fornices (anterior, posterior and lateral)
The cervical canal contains The internal and external os The hymen

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11
Q

cervix anatomy- internal os

A
  • The opening of the cervix into the body of the uterus
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12
Q

cervix anatomy- external os

A
  • The opening of the cervix into the vaginal.
  • Its shape and size varies widely with age, hormonal state and if a woman has had a vaginal birth.
  • In non parous women it is a small circular opening
  • In parous women it is wider
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13
Q

what are the fallopian tubes and their function?

A
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14
Q

what is the anatomy of the fallopian tube?

A
  • Infundibulum – funnel shaped segment
  • Ampulla – longest segment
  • Isthmus – thicker walled segment close to the uterus
  • The fallopian tubes are approximately 10cm in length and 1cm wide
  • They run laterally from the uterus through the peritoneum
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15
Q

blood supply to the fallopian tubes?

A
  • Blood supply is from branches of the ovarian and uterine
  • arteries
  • Blood drainage is via the ovarian and uterine veins
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16
Q

how do the fallopian tubes work?

A
  • An oocyte is released from the ovary into the
    peritoneal cavity
  • The fimbriae of the tubes drape over the ovary
  • The oocyte is captured by the fimbriae and swept into the tube
  • Cilia line the fallopian tubes
  • The cilia move in a beating movement in the direction of the uterus to create current in the surrounding peritoneal fluid towards the ampulla
  • The smooth muscles of the fallopian tube generate peristalsis movements which move the ovum along the tube towards the uterus
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17
Q

what are the 2 main functions of the ovaries?

A

Oogenesi:

  • production and release of mature ova (egg)

Endocrine function:

  • Secretion of hormones

-Oestrogen

-Progesterone

18
Q

what is the basic anatomy of the ovaries?

A
  • Bilateral, almond shaped organs situated laterally in the peritoneal cavity
  • Measure approximately 3x3x2cm but size depends on age and hormonal status
  • Double in size during pregnancy
  • Smaller and then atrophic during / after menopause
19
Q

what is each ovary divided into?

A
  • An outer fibrous coat
  • Cortex – contains up to 2 million primary oocytes at birth
20
Q

how many follicles mature each cycle, and what happens to the others>

A
  • Approximately 10 mature each cycle, only 1 becomes the dominant follicles
  • The primary follicle becomes the Graafian follicle
  • The other follicles close down Medulla
  • The central part containing blood vessels, lymphatic vessels and nerve
21
Q

what are the ovaries held by?

A

They are held in place by ligaments that anchor them to the pelvis wall and uterus. They are suspended in a double fold of the peritoneum called mesovarian.

22
Q

blood and nerve supply to the ovaries

A
  • Nerve supply to the ovaries runs with the vasculature and enters at the hilum
  • Lymphatic drainage is to the lateral aortic and iliac nodes
  • Blood supply is via the ovarian artery which branches form the descending aorta
  • The ovarian artery and vein enter at the hilum
  • Left ovary drains into the left renal
    vein
  • The right ovary drains into the inferior vena cava
23
Q

what is the pathophysiology of follicle development

A
  1. small groups of follicles mature under the influence of FSH after puberty.
  2. follicle develops from primordial f, to a secondary f and then 1 f becomes the tertiary or Graafian f.
  3. the Graafian f contains primary oocyte and fluid
  4. primary oocyte divides by meiosis to form secondary oocyte- released into abdominal cavity (ovulation).
  5. Graafian f ruptures and released oocyte is caught and transported to uterus
  6. tissue left from Graafian f forms into mass called corpus lute, this will persist if there is fertilisation and implantation, or regress into fibrous scar.
24
Q

what is it like imaging the ovaries using ultrasound

A
  • On ultrasound the ovaries look like elliptical / oval structures with an echogenic focus.
  • During the early menstrual cycle, multiple anechoic follicles can be seen
25
what is the menstrual cycle
a monthly series of hormonal changes that prepares the body for pregnancy.
26
what hormones are involved In the menstrual cycle
- Pituitary hormones * Follicle stimulating hormones (FSH) * Luteinizing hormone (LH) - Ovarian hormones * Oestrogen * progesterone
27
what 2 cycles does the menstrual cycle consist of?
- The uterine cycle -The menstrual, proliferative and secretory phases - The ovarian cycle- The follicular phase, ovulation and the luteal phase
28
what is the purpose of ovarian hormones
- The purpose of ovarian hormones are to -Produce a mature ovum for fertilisation -Prepare the endometrium for the fertilised ovum -Support an early pregnancy
29
days 1-4 of menstruation conissts of what cycles?
uterine cycle and ovarian cycle
30
what is the uterine cycle
- The endometrium is shed as hormonal support is withdrawn - Vaginal bleeding occurs - Myometrial contractions - Rising oestrogen levels stimulate growth of new endometrium
31
what is the ovarian cycle 1-4
- Called the follicular phase - Menstruation lasts approximately 1-7 days - FSH and LH are released from the pituitary gland, this induces development of the follicles - The ovarian follicles produce oestradiol and inhibin- this supresses FSH - As a result normally only 1 oocyte develops and the dominant follicle forms
32
day 5-13 proliferative uterine cycle
- Hormones from the hypothalamus stimulate FSH and LH release from the pituitary gland - There is proliferation of the cells in the endometrium causing thickening.
33
day 12-15 peri ovulatory - uterine cycle
- Pituitary and hypothalamus cause LH levels to rise sharply - Ovulation occues 36 hours after the LH surge
34
day 12-15 peri ovulatory- ovarian cycle
Ovarian cycle- Called ovulation - Increased levels of oestradiol reach a maximum on ay 13 - LH levels rise sharply, Ovulation occurs 36 hours after the LH surge. Endometrium has a 3 line sign – hypoechoic
35
day 15-28- secretory uterine cycle
Uterine cycle - The ovarian corpus luteum produces progesterone and oestradiol - Progesterone levels peak around day 21 causing changes in the endometrium – blood supply increases and cells enlarge - Without fertilisation the ovarian corpus luteum fails and progesterone and oestrogen levels fall - Hormonal support is withdrawn - The endometrium breaks down and menstruation occurs
36
day 15-28 secretory- ovarian cycle
Following release of the ovum, the dominant follicle becomes the corpus luteum. The corpus luteum produces oestradiol and increasing levels of progesterone. This peaks around day 21
37
summarise normal ovarian cyclical changes
- Normal ovary develops follicles (1-2mm) every 28 days - The dominant follicle develops (follicular phase) - The dominant follicle ruptures mid cycle at ovulation as LH reaches a peak and oestrogen levels are high (ovulatory phase). - After ovulation the corpus luteum forms (early luteal phase) - Without fertilisation the corpus luteum regresses (late luteal)
38
ovarian changes over time- postmeonopausal ovaries
Decrease in size with age – often hard to see on US
39
ovarian changes overtime- premenarchal ovaries
- Best viewed transabdominally - Look like small structures - During adolescence there is a growth of follicles which can be mistaken for polycystic ovaries
40
ovarian changes overtime- reproductive age ovaries
Changes occur due to hormone fluctuations
41