Female Reproductive #2 Flashcards
How is negative feedback to LH exerted in Luteal Phase?
⬆️Progesterone
How is negative feedback to FSH exerted in LUTEAL PHASE?
INHIBIN B!!
This part of the menstrual cycle is ALWAYS CONSTANT?
- LUTEAL (15 days)
Order of estrogen potency?
Estradiol > Estrone > Estriol
Primary estrogen secreted by the ovarian follicule?
Estradiol
Main estrogen converted peripheraly by aromatase and its the predominant estrogen in menopause?
Estrone
Estrogen produced by the placenta from circulating androgens?
Estriol
Main clinical signs of Polycystic Ovarian Syndrome ?
- Infertility
- Hirsutism
- Obesity
- Insulin resistance
- Amenorrhea/Oligo
Main hormones elevated in PCOS?
- ⬆️LH
2. ⬆️DHEA
In PCOS, why is FSH suppressed?
- ⬆️Levels of estrone (weak estrogen) —> ⬇️FSH
Mainly, why is there ⬆️Androgens in PCOS?
⬇️Aromatase activity —> ⬆️androgens and ⬇️estrogen
How to differentiate hirsutism of Adrenal from ovarian origin?
- Dexamethasone test—> ⬇️DHEA (Adrenal)
When does pregnancy usually occur?
8-25 hours after ovulation
When does implantation usually occur?
5-7 days after fertilization
LH and hCG have similar activity, why?
They share same Beta-subunit