Female Repro Histology

Question 1

Ovary Layers with Description

Answer 1

Medulla: Vascularized center with nerves and lymphatics

Cortex: Houses Follicles

Tunica Albuginea: connective tissue around cortex

Germinal Epithelium: Simple squamous to cuboidal

Question 2

Primordial Follicle Description

Answer 2

Develops in 5th month independent of hormones and arrested in prophase

Surrounded by simple squamous layer

Question 3

Primary Follicle Description

Unilaminar and Multilaminar

Answer 3

Unilaminar: Simple cuboidal layer and Zona Pellucida

Multilaminar: Multiple cuboidal layers called Granulosa Cells, Zona Pellucida thickens
Theca Interna with LH receptors that secretes androgen precursors
Theca Externa made of connective tissue

Question 4

Secondary Follicle Description

Answer 4

Antrum forms, Zona Pellucida thickens, Granulosa cells increase

Question 5

Graafian Follicle Description

Answer 5

Meiosis I finished before ovulation
Corona Radiata forms
Cumulus Oophorus prepared for ovulation
Mural Granulosa cells line follicle and secrete estrogen

Question 6

Follicular Atresia

Answer 6

Follicles that aren’t ovulated undergo apoptosis

Identified by folded zona pellucida and glassy membrane

Question 7

Ovarian Cycle Ovulatory Phase Description

Answer 7

LH surge triggers follicle to finish Meiosis I
Causes follicle to extend as a stigma that ejects oocyte
Corpus Hemorrhagium becomes the Corpus Luteum

Question 8

Ovarian Cycle Luteal Phase

Description and Cell Products

Answer 8

Luteinization of theca/granulosa cells of corpus hemorrhagium
Granulosa cells make Progesterone, Estrogen and Inhibin
Theca cells make androstenedione

Without fertilization, CL becomes corpus albicans

Question 9

Ovarian Cycle Phase Hormone Levels

Answer 9

Follicular phase has higher FSH and Estradiol

Ovulatory phase has higher LH and Progesterone

Question 10

Uterine Tube Cell Types

Answer 10

Ciliated Cells: stimulated by estrogen to move oocyte
most numerous in infundibulum and ampulla

PEG Cells: stimulated by progesterone to produce nutrient rich fluid

Question 11

Ovarian Cycle Phase Hormone Levels

Answer 11

Follicular phase has higher FSH and Estradiol

Ovulatory phase has higher LH and Progesterone

Question 12

Uterine Tube Cell Types

Answer 12

Ciliated Cells: stimulated by estrogen to move oocyte
most numerous in infundibulum and ampulla

PEG Cells: stimulated by progesterone to produce nutrient rich fluid

Question 13

Uterus Layers

Answer 13

Endometrium: Stratum Basalis and Stratum Functionalis

Myometrium: Stratum Vasculare

Perimetrium: Outer Serious Layer, continuous with peritoneum

Question 14

Uterus Blood Supply Breakdown

Answer 14

Uterine A. to Arcuate As. to Radial As. to Straight As to Spiral As.

Question 15

Menstrual Cycle Menstrual Phase

Description and Ovarian Cycle Correlation

Answer 15

CL regression decreases Estrogen and Progesterone
Stratum Functionalis to degrade until only Basalis left

Occurs during days 1-5 with Follicular Phase

Question 16

Menstrual Cycle Proliferative Phase

Description and Ovarian Cycle Correlation

Answer 16

Epithelium regenerates, Stromal cells proliferate, Spiral As lengthen, glands are short

Occurs during days 6-14 with Follicular Phase

Question 17

Menstrual Cycle Secretory Phase

Description and Ovarian Cycle Correlation

Answer 17

Glands become tortuous and filled with ground substance

Occurs during days 15-28 with Luteal Phase

Question 18

Cervix

Layers, Cell Types

Answer 18

Endometrium: No Spiral As and different function

Ectocervix: Stratified squamous cells, continuous with vagina

Endocervix: Simple columnar cells, secretions regulated by estrogen

Question 19

Human Papilloma Virus

Description and Diagnosis

Answer 19

Infects immature basal squamous cells

Diagnose with pap smear

16 and 18 carry high risk of cervical cancer

Question 20

Vagina Layers

Answer 20

Stratified Squamous mucosa with no glands

Adventitia has Inner Dense connective tissue with elastic and outer loos connective tissue