Female Repro Flashcards
Define estrus
Fertile window where mating can lead to pregnancy
What is the post fertile phase where progesterone is highest? hint: it is the longest phase
Diestrus
Define Proestrus
Initial phase that is marked by vulva bleeding and swelling
What is the prolonged period of sexual inactivity?
Anestrus
Which hormone surges before ovulation?
LH
Follicular maturation occurs during which phase?
Proestrus
During which phase does the CL start to develop?
Metestrus
What releases GnRH?
Hypothalamus
The anterior pituitary is also called:
Adenohyphosis
Where does GnRH bind to?
GnRH receptors in the AP
What specifically secretes FSH and LH?
Basophils
Which hormone regulates the onset of puberty, sexual development and ovulatory cycle?
GnRH
Which hormone stimulates follicular development ?
FSH
FSH stimulates which specific cells in the ovary ?
Granulosa cells
What do granulosa cells synthesize that converts androgens to E2?
Aromatase
What does LH do?
Stimulates theca cells to make androgens
What promotes positive feedback for LH?
Estrogen shutting off
What inhibits LH?
Estrogen
What is secreted by granulosa cells?
E2
What stimulates the secretion of LH ?
GnRH as a result of E2 from the dominant follicle
What is the function of P4?
Prepare endometrium for implantation embryo nourishment
What does P4 inhibit during pregnancy?
Lactation and decreases uterine contractions
If there is no pregnancy, what happens to P4 levels?
Drop
What cause an increase in P4 secretion by the CL/
LH surge
What hormones can P4 inhibit?
LH, FSH, GnRH
AMH is produced bu which cells in the ovary?
Granulosa
When does AMH secretion lower?
When selection of the dominant follicle occurs
How can you check for ovary remains?
By checking AMH levels/presence
Which part of the ovary contains the follicles?
Cortex
Loose connective tissue is a characteristic of which part of the ovary?
Medulla
Cellular CT is a characteristic of which part of the ovary?
Cortex
What type of epithelium covers the ovary?
Germinal epithelium
Describe the germinal epithelium
Simple cuboidal
What lies between the germinal epithelium and the cortex?
Tunica albuginea
Describe the function of the ovary
Gamete and steroid hormone production
What is the Tunica albuginea made of?
Dense CT
What 2 things make up the cortex?
Stroma and parenchyma
Which part of the cortex is the functional part (i.e. where the follicles reside?
Parenchyma
Describe the cells in the stroma
Spindle shaped with elongated nucleus
Stroma is considered _____________ (supportive or functional)
Supportive
What are the 3 ovarian follicles that can be identified on their developmental stage?
- Primordial
- Growing (primary and Antral)
- Mature (Graafian)
What is the oocyte surrounded by a simple layer of squamous cells called? They are found in the stroma
Primordial follicle