Female reporductive Flashcards
Space of Rezius. How is bladder displaced with a mass in this space?
Extraperitoneal potential space b/w pubic symphysis and bladder. Mass in space will displace bladder posteriorly. Pelvic/abdominal mass will displace bladder inferiorly/anteriorly.
How are cervix and bladder attached
Cervix attached to posterior edge of bladder by the parametrium.
True and false pelvis seperatied by:
Linea terminalis (bony landmark) which is a composite of the arcuate line of the ilium, iliopectinal line, and pubic crest
What organs are in true pelvis and false pelvis?
True pelvis usally has uterus, ovaries, and body of bladder. Dome of bladder is in false pelvis.
Gynecologic cysts (4)
Nabothian. Gartner duct cyst (anterior vagina). Bartholin gland cyst (posterior (Bartholin near Butthole). Skene gland cyst (anterior)
Associations w/ unilateral kidney (women)
Unicornuate uterus +/- rudimentary horn.
Explain etiology of bicornuate uterus vs. septate uterus
Bicorneaute uterus, the 2 uterus halves fail to fuse correctly. In sepatate uterus, they fuse correctly, but the septum doesn t cleave completely
Bicornea uterus vs. septate uterus differentiation
look at fundus of uterus. Bicornuate is more heart shaped. Septate is just normal shaped.
Didelphys uterus vs. bicorneate
Didelphys is complete failure of fusion. Bicorneate is partial failure of of fusion.
Fertility issues in bicronuate uterus and septate uterus
Bicornuate uterus has no fertility issues (because its all endometium in there). Septate uterus has fertility issues (because septum is not endometrium)
American Fertility society classification of mullerian duct abnormalities (Class 1-7)
- uterine agenesis/hypoplasia. 2. unicornuate uterus. 3. Didelphys. 4. Bicornuate. 5. Septate. 6. Arcuate (normal variant). 7. Diethylstilbestrol (DES) uterus (hypoplastic/T-shaped.
HSG contraindications
contrast allergy, infection,pregnancy.
Salpingitis isthmica Nodosa (SIN) (aunt Minnie).
Nodular scarring of fallopian tubes, likely post inflammatory/infectious, a/w infertility and ectopic pregnancy.
Uterine anatomy on T2 MR (intensity of 3 layers)
Endometrial stripe; T2 hyperintense. Junctional zone; very T2 hypointense. Outer myometrium; mildly T2 hypointense
Benign (2) and malignant (1) uterine disease
Adenomyosis, leiomyoma. Endometrial cancer.
Cyclical endometrial thickness
1-4 (menstrual phase) <4mm. 5-9 Early proliferative; 4-8mm. 10-14 later proliferative; 6-10mm. 15-18 (secretopy phase); 7-14mm.
Hormonal dominance by phase of menstrual cycle
Proliferative phase: estrogen. Secretory phase: progesterone.
Causes for thickened endometrium (3)
Endometrial polyp, tamoxifen effect, endometrial cancer/postmenopausal thickness.
Endometrial polyp. What is a more definitve test for diagnosis? How large is too large?
Sonohystogram is helpful for diagnosis. If over 1.5, concerning for malignancy.
Tamoxifen changes. How thick can it get? How often to screen for cancer?
Tamoxifen is estrogen agonist no uterus. Causes endometrial hyperplasia, metaplasia, and carcinoma. Subendometrial cysts and endometrial polyps. Tamoxifen changes can be as thick as 8mm. Ulstrasound screening every 6 mont.s
Endometrial cancer - 2 demographic peaks
- Perimenopausal (estrogen dependent, better prognosis). 2. Older(70 s), spontaneous froma trophic changes. Bad prognosisl
Endometrial cancer staging
1.A endometrium 1.A.. Myometrium less than 50%. 1B. Myometrium More than 50%. 2. Cervix. 3. Outside Uterus. 4. Bladder/Rectum.
Endometiral staging - critical stage
Stage 1B; More than 50% of myometrium. At this stage, patients are more likely to have a Positive lymph node. Will get lymph node dissection, and possible Pelvic radiation.
Risk factors for endometrial cancer
Nullparity, hormone replacement, tamoxifen.
Endometrial thickness that necessicatates biopsy in post-menopausal woman with bleeding and without.
With bleeding; >4mm = biopsy. W/0 bleeding: >8mm = biopsy.
Myometial masses
Leyomyoma, leiomyosarcoma
Leiomyoma MR appearance
T2 hypointense with distinct margins. However if cystic/myxoid degeneration, then it may be heterogenously T2 hyperintense. If there is cavernous or hemorrhageic degeneration, it may be T1 hyperintense.
Leiomyoma MR mimic
Uterine contraction.
Leiomyoma on u/s.
Heterogenous, hypoechoic uterine mass w/ linear bands of shadowing.
Leiomyoma Locations in uterus
Intramural, submucosal, subserosal, cervical
Variant of leiomyoma w/ fat
Lipoleiomyoma.