fed and fasted states Part 1 NOT FINISHED Flashcards
How much glucose does the brain consume per day?
120g
Below what concentration of glucose is critical to the brain? why?
~2 mM
as the glucose concentration in the blood approaches the KM, the rate of glucose transport into the brain slows down
KM of GLUT3 in the brain is 1.4mM
What happens if the blood glucose concentration becomes too low? (brain)
brain becomes starved and hypoglycaemia follows
What does the body do to counteract blood glucose concentration becoming too low
Glycogen reserves in the liver can be
mobilised but this isn’t enough.
Animals synthesise glucose from
pyruvate, glycerol and amino acids. using gluconeogenesis
How do we synthesise glucose
gluconeogenesis
Where is the main site of gluconeogenesis
Liver
What do only animals use to synthesise glucose?
Lactate
How is lactate used to synthesise glucose
From muscles converted into pyruvate and used in Krebs cycle/ citric acid cycle and become phosphoenolpyruvate via oxaloacetate and then glucose 6 phosphate to make other thingd
What do both plants and animals use to synthesise glucose?
Glycerol
What do only plants use to synthesise glucose?
Fixing co2
How is glycerol used to synthesise glucose
From triacyl-glycerols glycerols can be put in glycogenesis
What cannot be use to synthesise glucose
Fatty aids
How is fixing co2 used to synthesise glucose
Co2 fixation convert to 3- phospho-glycerate
What can be formed from glucose in plants only
Starch
Sucrose
What can be formed from glucose in animals only
Glycogen
Blood glucose
