Feb. 25th - Temperature Tolerance Flashcards
Stress tolerance
return to homeostasis
membrane fluidity
extent of molecular disorder and molecular motion within a lipid bilayer
gel phase
(solid)
phospholipid tails are tightly packed together
liquid crystalline phase
(fluid (optimal))
phospholipid tails can move around
protein isoforms
slightly different structures (AA sequences)
may have dif. relationships with temp
(this can be good for important proteins)
Strategies of temperature stress tolerance
1: alter composition of macros to preserve function
2: accumulate molecules to protect membranes and proteins
Preserving function under temp stress by altering macros composition
maintain protein flexibility and membrane fluidity (lcs)
ex. isoforms … cells can change which isoforms are active/ synthesized at dif temps.
(ex. cold-adapted myosin in fish)
Accumulating molecules to protect membranes and proteins under temp stress
ex. cryoprotectants at low temps!
glycerol, trehalose, proline
cryoprotectants
molecules that protect cells’ proteins and membranes under extreme cold/ dehydrating conditions