Fatty Acid Synthesis (Lipogenesis Pt. 1) Flashcards
1
Q
where does fatty acid synthesis occur
A
the cytosol of liver cells
2
Q
what are the five stages?
A
- loading
- condensation
- reduction
- dehydration
- reduction
3
Q
what is the starting molecule
A
pyruvate
4
Q
where does the pyruvate come from
A
it is formed from oxaloacetate and acetyl CoA in the mitochondria (TCA)
5
Q
what happens if there is extra pyruvate that is not being used in lipogenesis
A
it is turned back into oxaloacetate via citrate lyase, then pyruvate again, and returns to the mitochondria as oxaloacetate and acetyl CoA
