Fatty Acid Metabolism Flashcards
Anhydrous
Contains no water.
Bile Salts
Highly amphipathic cholesterol derivatives containing a charged acidic group.
What do bile salts do?
Break down fat globules.
How do animals store chemical energy?
Lipids.
Chylomicrons
Packaged lipids and proteins that travel through the lymph system.
Steps of Fatty Acid Synthesis
- Joining Reaction
- Reduction
- Loss of Water
- Reduction
Steps of Fatty Acid Oxidation
- Oxidation
- Gain of Water
- Oxidation
- Splitting Reaction
Where are fatty acids catabolized?
Mitochondria.
What vitamin carries activated long chain fatty acids into the mitochondria?
Carnitine.
Where does fatty acid beta-oxidation take place?
Mitochondrial Matrix.
Four recurring reactions in fatty acid beta-oxidation.
- Oxidation by FAD
- Hydration
- Oxidation by NAD+
- Thiolysis by CoA
What are the products for each cycle of beta-oxidation?
FADH2
NADH and H+
Acetyl CoA
Acyl-CoA (fatty acid shortened by 2 carbons)
In the first reaction of fatty acid metabolism, acyl-CoA is oxidized by ________?
Acyl-CoA dehydrogenase
In the second reaction of fatty acid metabolism, enoyl-CoA is hydrated by ________?
Enoyl-CoA hydratase
In the third reaction of fatty acid metabolism, the C3 carbon is oxidized by ________?
L-3-hydroxyacyl CoA dehydrogenase