Fatty Acid And Cholesterol Metabolism Flashcards

0
Q

endogenous fats) liver –> peripheral Hssues

A

VLDL

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1
Q

exogenous fats) small intesHnes –> peripheral Hssues

A

Chylomicrons

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2
Q

bad cholesterol”) VLDL –> peripheral Hssues

A

LDL

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3
Q

good cholesterol”) peripheral Hssues –> liver

A

HDL

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4
Q

Surrounding the heart is a layer of fat called the

A

Pericardial fat

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5
Q

Protect the kifneys

A

Perinephric fat

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6
Q

n. a lipoprotein particle present in the blood after digested fat has been absorbed from the small intestine

A

Chylomicron

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7
Q

an enzyme that catalyses the hydrolysis of triglycerides in chylomicrons and very low-density lipoproteins to free fatty acids, which are absorbed from the capillaries into local tissues

A

Lipoprotein lipase

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8
Q

Help activate lipoprotein lipase

A

Apolipoprotein C II

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9
Q

From the intestinal lymphatic system the chylomicrons are transported to the

A

Thoracic duct

Cisterna chyli

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10
Q

Contain relatively having more cholesterol after passing through the adipose cells which extract the triglycerides, go to the liver for further processing

A

Chylomicrons remnants

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11
Q

Ito lang yung sa cytosol nangyayare

A

Glycolysis
Pentose phosphate pathway
Fatty acids synthesis

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12
Q

Rate limiting enzyme in PPP

A

Glucose-6-phosphate_dehydrogenase

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13
Q

Rate limiting enzyme of cholesterol synthesis

A

HMG CoA Reductase

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14
Q

Rate limiting enzyme of fatty acid synthesis

A

Acetyl CoA Carboxylase

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15
Q

Rate limiting enzyme beta oxidationor fatty acids

A

Carnitine acyl transferase I

16
Q

Rate limiting enzyme of glycolysis

A

Phospofructokinase 1

17
Q

Rate limiting enzyme of gluconeogenesis

A

Fructose 1,6-Biphosphotase

18
Q

Rate limiting enzyme of glycogen synthesis

A

Glycogen synthase

19
Q

Rate limiting enzyme of glycogenolysis

A

Glycogen phosphorylase

20
Q

Rate limiting enzyme of pentose phosphate pathway

A

HMP Shunt - G6PD

21
Q

Rate limiting enzyme of lipolysis

A

Hormone sensitive lipase

22
Q

Rate limiting enzyme urea cycle

A

Carbamoyl phospahte synthase I

23
Q

Rate limiting enzyme of purine metabolism

A

PRPP Amidotransferase

24
Rate limiting enzyme of pyrimidine metaolism
Carbamoyl phospahte synthase II
25
Rate limiting enzyme of heme synthesis
ALA synthase
26
Rate limiting enzyme of Ketone body synthesis
HMG CoA lyase
27
Rate limiting enzyme of TCA
isocitrate dehydrogenase
28
Substrate in TCA cycle
Pyruvate
29
First five step in glycolysis
Investment phase
30
Last five step in glycolysis
Payoff phase
31
Glycolysis produce
4 ATP | 2 NADH
32
Pyruvate to acetyl coa
Pyruvate dehydrogenase complex
33
How many carbon in pyruvate and acetyl coa
3 and 2 respectively
34
Combination of acetyl coa and oxaloacetate then to what
Citrate
35
These are normal products of lipid metabolism and can be used to provide energy.
Ketogenesis