Fats and performance Flashcards

1
Q

After what time are carbohydrates a limiting factor in exercise?

A

> 90 mins

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2
Q

Which is an alternative to delay fatigue?

A

to increase the capacity to oxidise fat

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3
Q

What are some advantages of lipids over CHO?

A
  • Greater energy density
  • Most efficient way of storing energy in limited space
  • More ATP per molecule (147 vs 38)
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4
Q

What is the primary function of white fat (WAT)?

A

energy storage (triglycerides)

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5
Q

What are the two different WAT depots?

A
  • Subcutaneous (scWAT)
  • Visceral (vWAT)
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6
Q

Explain brown fat (BAT)

A

Metabolically active tissue, oxidises CHO and lipids to generate heat.
Central nucleus and a high density of mitochondria

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7
Q

Explain beige fat (brite)

A
  • Only found in scWAT
  • Generate energy in the form of heat, contributing to thermogenesis
  • High degree of spasticity, revert to WAT in the absence of stimuli
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8
Q

True or False
Lower-body adipocytes (scWAT) tend to expand via hyperplasia

A

True

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9
Q

True of False
Upper-body adipocytes (vWAT anterior abdominal wall region) expand via hypertrophy

A

True

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10
Q

What is hyperplasia?

A

Increase in the number of fat cells

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11
Q

What is hypertrophy?

A

Increase in size of cells

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12
Q

What are some differences in MFO and fatmax between groups?

A
  • MFO was greater in trained groups
  • Absolute MFO were greater in males than females
  • Fatmax was greater in females compared to males
  • Prior CHO feeding tends to reduce MFO and Fatmax
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13
Q

Increases in vWAT are correlated with:

A
  • Impaired glucose tolerance
  • Increased insulin resistance
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14
Q

Increases in scWAT are correlated with:

A
  • Decreased metabolic risk
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15
Q

True or False
Long term exercise increases fatty acid oxidation in human WAT

A

True

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16
Q

which exercise intensity oxidise the most fat?

A

65% VO2max in trained
55-72% VO2max well conditioned cyclist
43-61% VO2max in obese individuals

17
Q

Where are the intramuscular triglycerides (IMTG) located?

A

adjacent to mitochondria in trained muscle

18
Q

What is associated with insulin resistance in obese/sedentary individuals?

A

Intramuscular triglycerides (IMTG)

19
Q

What is the main source of fat oxidation at moderate to high exercise intensities?

A

Intramuscular triglycerides (IMTG)

20
Q

What is the difference between maximal fat oxidation and Fatmax?

A
  • Maximal rate of fat oxidation (MFO) (g.min-1) is the point at which the body’s use of fatty acids (FAs) for energy is at its highest.
  • Fatmax: exercise intensity at which MFO occurs (% VO2max)
21
Q

What are the main differences in exercise-induced adaptations in WAT compared with BAT in man?

A
  • long term exercise increases fatty acid oxidation in human WAT
  • Glucose uptake: Exercise increases glucose uptake in WAT, but does not affect glucose uptake in BAT.
  • Endocrine activity: Exercise increases endocrine activity in both WAT and BAT.
22
Q

Where does ketogenesis occurs?

A

In mitochondria of liver cells

23
Q

Briefly outline the factors that affect IMTG use for fuel during exercise

A

Exercise duration
Training status
Diet
Hormones

24
Q

What are the 3 ketone bodies synthesised in ketogenesis?

A
  • acetoacetate (AcAc)
  • beta-hydroxybutyrate (BOHB)
  • acetone
25
Q

Explain some facts about Keto Diet (KD)

A
  • <50g CHO/day 60-80% kcal from fats and 1.2g.kg/d protein
  • keto adaptation may take 2-4 weeks
  • increased fat oxidation but impairs glycolytic pathways
  • no performance benefit
  • may be effective to reduce body weight and fat mass (in the short term)
26
Q

Explain fat adaptation

A
  • may result in metabolic alterations favouring fat oxidation
  • not improved exercise performance
27
Q

What is ketogenesis?

A

A catabolic pathway of metabolism. Fatty acids and certain ketogenic amino acids are broken down to derive energy by alternative means. Ketone bodies are produced in the process.

28
Q

Reason for why endurance training results in increased capacity to oxidise fats during mild-moderate intensity exercise

A

Regular aerobic exercise promotes training induced adaptations such as increased activity of lipoprotein lipase an increased capillarisation in trained muscle