fastidious gram negative rods Flashcards
fastidious gram negative rods are cultured on ___ agar
chocolate
bartonella spp.: name the four species
b. bacilliformis, b. quintana, b. henselae, b. clarridgeiae
b. bacilliformis: clinical presentations
carrion’s disease = oroya fever (high fever = severe anemia due to RBC infection)
character skin rash
spread by sandflies
b. quintana: clinical presentations
trench fever, aids related conditions, endocarditis
b. henselae: clinical presentations
cat scratch disease, aids related condition, endocarditis
b. clarridgeiae: clinical presentations
cat scratch disease
bartonella spp.: diagnosis
serology, histology, culture
haemophilus influenzae: culture
chocolate agar
haemophilus influenzae: character
requires hemin (X factor) and NAD (V factor) to grow
throat carriage
haemophilus influenzae: transmission
respiratory droplets, close contact
haemophilus influenzae: virulence factors
some strain possess antiphagocytic capsules (a-f, b is the most common; also in sg the most common type is the non encapsulated type)
haemophilus influenzae: clinical presentations
encapsulated infections: meningitis, acute epiglottitis, septicaemia, cellulitis, pneumonia, osteomyelitis, septic arthritis
non-encapsulated infections: invasive (meningitis and septicaemia in neonates; pneumonia in older age groups) and non-invasive (urti)
haemophilus influenzae: diagnosis
blood culture
haemophilus influenzae: treatment
ceftriazone; most species are resistant to penicillin since they produce beta lactamase
haemophilus influenzae: prevention
conjugate vaccines against type b for children and at risk patients
chemoprophylaxis of rifampicin and vaccine for prevention of secondary cases
haemophilus ducreyi: histology + character
“shoal of fish” appearance
x (iron, hemin) dependent growth
haemophilus ducreyi: culture
chocolate agar
haemophilus ducreyi: transmission
sexually transmitted disease
haemophilus ducreyi: clinical presentations
chancroid (painful genital ulcer + enlarged inguinal lymph nodes that may suppurate and ulcerate)
haemophilus ducreyi: diagnosis
culture, pcr
haemophilus ducreyi: treatment
several agents effective
hacek group
group of gram negative bacteria associated with endocarditis
haemophilus parainfluenzae aggregatibacter actinomycetemcomitans cardiobacterium hominis eikenella corrodens kingella kingae
klebsiella granulomatis: transmission
sexually transmitted disease
klebsiella granulomatis: clinical presentations
granuloma inguinale = donovanosis
subcutaneous nodules break down to painless ulcers, gradual enlargement of ulcers with prominent granulation tissue, tissue loss and scarring
spread to inguinal region causes periadenitis (pseudo bubo) and pelvic fibrosis