Farm animal Neuro Flashcards
What should we ask in the Hx of farm animal neuro?
who is affected (age, signalment)
how many affected
onset sudden vs gradual
other CS? systemic dz with neuro signs?
tx attempted and effective?
epidemiological hx?
management hx?
What do we observe in a farm animal neuro exam?
head carriage
facial symmetry
stance
posture
gait
interaction with other animals
reaction to stimuli
What are potential clinical signs of cerebral problems in FA?
dullness
depression
hyperaesthesia
opisthotonus
blindness (intact plr)
compulsive walking/circling
contralateral proprioceptive defects
What are potential clinical signs of cerebellar problems in FA?
loss of fine motor control
tremor
ataxia
dysdiadochokinesis
loss of menace reflex
What are the potential clinical signs of brainstem problems in FA?
signs dependent on which cranial nerve affected
RAS (dullness)
pyramidal system (ipsilateral weakness, contralateral extensor thrust)
What are the potential clinical signs of hypothalamic problems in FA?
blindess
loss of accomodation
hyperaesthesia
aggression
disorientation
changes in appetite
thermoregulation
How can we localise lesions in the spinal cord?
proprioceptive responses: paper slide, hopping
withdrawal responses
panniculus reflex
perineal reflex
myotatic reflexes: patellar, ECR, gastrocnemius, triceps
What does a blood stained CSF indicate?
recent haemorrhage or artefactual due to iatrogenic damage of vessels within spinal canal
What does a xanthochromic appearance of CSF indicate?
yellow/orange discoloration is indicative of past haemorrhage
haemosiderophages may be seen among cells
What does frothy appearance of CSF indicate?
protein content is increased
What does turbidity of CSF indicate?
cell count much higher than normal
What are the clinical signs of bacterial meningoencephalitis?
most frequent in neonates
dullness
altered mentation
odd vocalisations
gait change
head pressing
blindness
lateral recumbency
opisthotonos
convulsions
death
signs of septicaemia
signs of bacteraemia
What is the tx for bacterial meningoencephalitis?
antibiosis
anti-inflammatories
good supportive care
What is the prognosis and prevention for bacterial meningoencephalitis?
prognosis: poor
prevention: identify cause and correct problem
What are the clinical signs of lead poisoning?
from lead paint or discarded batteries
blindness
dullness
frenzy
bellowing
aggression
muscle fasciculations of head and neck
abnormal movements of head and eyes
staggering gait
convulsions
death
How do we dx and tx lead poisoning?
dx: blood/kidney tissue lead levels, can’t wait on diagnosis = tx on suspicion
IV calcium sodium edetate: precipitates lead and causes excretion
What is cerebrocortical necrosis CCN/ polioencephalomacia PEM?
disease of brain swelling in cattle sheep goats camelids
caused by shift of ruminal flora from thiaminogenic to thiaminolytic
due to too much concentrate feed, lush pasture, recent worming
6-12 week old lambs most at risk
What are the clinical signs of CCN/PEM?
early: blind, isolated, wander aimlessly, star gazing, dark green scour
later: pregress within 24h to seizures and death if untreated
How does CCN/PEM cause swelling of the brain?
decrease in ruminal pH
increases thiaminase producing bacteria in rumen
less thiamine (B1) available
affects glycolysis and kreb cycle
swelling and flattening of cerebral gyri
What are the post-mortem signs of CCN/PEM?
gyri pale and swollen
fluorescence under UV