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MCM > Fall 2018 MCM Final > Flashcards

Fall 2018 MCM Final Flashcards

1
Q

A nucleotide consists of

A

Heterocyclic nitrogenous base
sugar
phosphate

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2
Q

3 different kinds of nucleotides

A

Nucleoside mono/di/triphosphate

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3
Q

What is a nucleoside composed of?

A

Heterocyclic nitrogenous base

Sugar

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4
Q

What are the heterocyclic nitrogenous base of DNA?

A 
Adenine (A)
Guanine (G)
Cytosine (C)
Thymine (T)
Uracil (U)
Hypoxanthine(I)
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5
Q

The nucleotide bases have corresponding nucleoside names (base + the sugar), what are they?

A 
Adenosine
guanosine
Cytidine
Thymidine
Uridine
Inosine (this ones base is hypoxanthine)

Add an -INE

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6
Q

Name the 9 Purines

A 
Purine
adenine
guanine
hypoxanthine
xanthine
theobromine
caffeine
uric acid
isoguanine
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7
Q

Adenosine effect on CNS? What is a popular antagonist of adenosines receptor?

A

Inhibitory

Caffeine

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8
Q

Adenosine monophosphate is a core element of which coenzymes?

A

NAD+
FAD
CoA

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9
Q

What does caffeine metabolize into in the liver?

A

12% Theobromine
4% Theophylline
84% paraxanthine

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10
Q

Theobromine acts as what kind of inhibitor of phosphodiesterase?
Acts on the adenosine receptor how?

A

competitive nonselective phosphodiesterase inhibitor

nonselective adenosine receptor antagonist

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11
Q

What are the agonist and antagonists of A1, A2a, A2b, A3 adenosine receptors?

A

Adenosine

Caffeine and Theophylline

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12
Q

A1 adenosine receptor effect?

A

Decreased heart rate

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13
Q

A2A adenosine receptor effect?

A

Vasodilation

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14
Q

A3 adenosine receptor effect?

A

Cardiac muscle relaxation and cardioprotective

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MCM (2 decks)

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