Factoids

Question 1

What drugs are a2 agonists? Uses?

Answer 1

Clonidine: malignant HTN +/- renal dz (does not decrease renal perfusion), sedation

a-methyldopa: HTN in pregnancy

Question 2

What are the nonselective a-blockers? Uses?

Answer 2

Phenoxybenzamine: used to tx pheo because the block is irreversible

Phentolamine: tx of MAOi when they have eaten tyramine (reversible block)

Question 3

What are the a1-selective blockers? Uses?

Answer 3

Prazosin - HTN, urinary retention in BPH
Terazosin - ‘’
Doxazosin - ‘’

Tamsulosin - selective for a1-1A/1D on prostate –> BPH (no effect on BP, so used when pt has BPH but no HTN)

Question 4

What are the a2-selective blockers? Uses?

Answer 4

Mirtazapine - depression

Question 5

What dzs are treated with BB?

Answer 5

angina
MI
SVT
HTN
CHF
Glaucoma (timolol)

Question 6

BB that starts with A-M is __.

Answer 6

b1 selective

Question 7

BB that starts with N-Z is __.

Answer 7

non-selective (b1 and b2)

Question 8

What are the BB that are actually agonists?

Answer 8

Acebutalol and Pindolol are partial agonists

Question 9

What BB also block a1?

Answer 9

Carvedilol and Labetalol

Question 10

BB used for stage fright?

Answer 10

Propranolol

Question 11

BB CI in what?

Answer 11

Cocaine OD, asthmatic, diabetic (decreases glucose levels and blunts the symptoms of hypoglycemia)