F4 B6 CELL DIVISION Flashcards
State the 2 stages of cell division
- karyokinesis (division of nucleus)
- cytokinesis (division of cytoplasm )
What is cell cycle?
the sequence of events that involves DNA multiplication and cell division to produce 2 daughter cell.
What is mitosis?
the division of the nucleus of parent cell into 2 nuclei
Explain prophase in mitosis
- chromatin shorten and thicken
- both sister chromatids joined at the centromere
- nucleus membrane disintegrate
- nucleolus disappears
- centriole move to opposite poles
- spindle fibers form
Explain metaphase in mitosis
- centrioles at opposite poles of cell
- spindle fibers maintain chromosomes at equatorial plane
- chromosomes aligned in single row
- centromere begins to divide.
Explain anaphase in mitosis
- centromere divides into 2
- sister chromatids separate
- spindle fibers shorten, contract
- sister chromatids attracted to opposite pole
- chromatids arrives at pole of cell
Explain telophase in mitosis
- chromatids now called daughter chromosomes
- each pole contains 1 set of complete and identical chromosomes
- chromosomes shaped to fins chromatin threads
- nucleoli formed
- spindle fibers disappear
- new nucleus membrane formed
What is meiosis?
process of cell division that occurs in reproductive organs to produce gametes
Explain prophase I in meiosis
- chromatin shortens, thickens and forms chromosomes
- nucleus membrane & nucleoli disappear
- both centrioles move to opposite poles
- spindle fibers form
Explain metaphase I in meiosis
- homologous chromosome arranged at equatorial plane
- sister chromatids still tied together
- centromere not separated
Explain anaphase I in meiosis
- spindle fibers contract
- each homologous chromosomes separate from its homologous pair
- pulled to opposite poles
- sister chromatids still tied together
- centromere not separated
Explain telophase I in meiosis
- chromatids arrive at opposite poles
- spindle fibers disappear
- nucleoli reappear
- nuclear membrane formed
- cytokineses to produce 2 daughter cell. ( haploid )
Whats the point where the chromatids cross over?
chiasma
Explain prophase II in meiosis
- nucleoli and nuclear membrane disappear
- chromosome made up of sister chromatids
- spindle fibers from
Explain metaphase II in meiosis
- chromosomes arranged on equatorial plane
- each chromatid tied to spindle fibers at centromere
- centromere separates
Explain anaphase II in meiosis
- sister chromatids centromere separate
- sister chromatids separates & move towards opposite poles
- chromatids = chromosome
Explain telophase II in meiosos
- chromosomes at pole of cell
- spindle fibers dissapeared
- nucleoli formed
- nuclear membrane formes
- cytokinesis occur to produce 4 daughter cells. ( haploid )
What are the types of tumour?
- benign tumour ( not dangerous; surgically removed)
- malignant tumour ( cancer; radiation, chemical substance, carcinogens)
- cells divide continuously and develop a tumour.
- cancer cells spread & destroy normal cells
What will happen if any abnormality occurs during meiosis?
- down syndrome (47 chromosomes)
- spindle fibers failed to function in anaphase I/II
- chromosomes failed to function
- abnormal number of chromosomes ( 22,24 )
- extra at 21st set (trisomy 21)
- mental retardation, slanted eyes, protruding tongue.