ezcema/dermatitis Flashcards
what are the general symptoms of ezcema in the acute phase
papulvesicular
red lesions
oedema
ooze/scaling/crusting
what are the general symptoms of ezcema in the chronic phase
thickening/lichenification
elevated plaques
increased scaling
what is lichen simplex eczema, describe it
eczema caused by the patient scratching at the area
it will have very well defined edges
what is seborrheic dermatitis also known as, who gets it?
cradle cap
young children/babies
what is stasis eczema
this is eczema secondary to hydrostatic pressure, oedema and RBC extraversion
what is contact allergic dermatitis
type 4 hypersensitivity reaction
what causes contact allergic dermatitis
Langerhans cells in the epidermis processes antigen, the antigen is then presented to the Th cells in the dermis. The sensitised Th cells migrate into lymphatics then to regional nodes where antigen presentation is amplified. On subsequent antigen challenge the T cells proliferate and migrate and infiltrate the skin causing the dermatitis.
what is the investigation for contact allergic dermatitis
patch testing
what is irritant/ contact dermatitis
non-specific physical irritation not a specific allergic reaction
what causes irritant/ contact dermatitis
trauma (e.g. soap/ detergent, nappy)
what is the treatment of irritant/ contact dermatitis
avoidance of irritant
what is atopic eczema/dermatitis
eczema/dermatitis caused by a mutation
what causes atopic eczema/dermatitis
mutation in the filaggrin gene
what are the symptoms of atopic eczema/dermatitis
itch
ill-defined erythema and scaling (BUZZWORD)
flexural distribution
what are the chronic changes involved in atopic eczema/dermatitis
lichenification
skin picking
secondary infection