Eyedocs anatomy Flashcards
What is the space called in the centre of the hyaloideocapsular ligament (Weiger)?
Berger’s space
Where does Cloquet’s canal travel from?
Courses from Berger’s space posteriorly through the central vitreous
What structures pass through the foramen rotundum and foramen ovale?
Rotundum - CNV2
Ovale - CNV3, accessory meningeal artery
What structures pass through the internal acoustic meatus?
CN7 and CN8
Vestibular ganglion and labyrinthine artery
What structures pass through the jugular foramen? Nerves, Arteries, Sinuses
Nerves: CN9, CN10, CN11
Arteries: meningeal branches of occipital and ascending pharyngeal arteries
Sinuses: inferior petrosal sinus, sigmoid sinus,
Where are the motor nuclei of the cranial nerves?
CN I - no nucleus, originals from olfactory bulb
CN II - no nucleus, originates from retina
CN III - upper part of midbrain at level of superior colliculus
CN IV - lower part of midbrain at level of inferior colliculus
CN V - upper dorsal part of the pons
CN VI - lower pons, deep to facial colliculus in floor of fourth ventricle
CN VII - lower part of pontine tegmentum
CN IX, X, XI nucleus ambiguus in the medulla.
CN XII - below hypoglossal trigone in floor of fourth ventricle of upper medulla
How long is each optic nerve segment?
1. intraocular
2. orbital
3. intracanalicular
4. intracranial
- 1mm
- 25mm
- 4-10mm
- 10mm
Where is the inner capillary plexus of the retina located in?
The ganglion cell layer
What is the first order neuron of the sympathetic pathway of the pupil?
Hypothalamus along the brainstem to synapse in the ciliospinal centre of Budge
What is the second order and third order neuron of sympathetic pathway of pupil?
Second: Centre of Budge to superior cervical ganglion
Third: Superior cervical ganglion, travels along carotid plexus, branches join ophthalmic division of trigeminal nerve and pass through ciliary ganglion to nasociliary and short ciliary nerves
Where do they layers project to in the primary visual cortex?
Layer II/III: project to secondary visual cortex
Layer IV: receives fibres from macula
Layer V: projects to superior colliculus
Layer VI: Projects to LGN
What is the afferent pathway of the light reflex?
Retina –> optic chiasm –> cross into pretectal nucleus near superior colliculus in midrain
What is the centre of the light reflex? What is responsible for the consensual reflex
Fibres from both pretectal nuclei go and connect with the edinger westphal nucleus via INTERNUCIAL NEURONS
What is the efferent pathway of the light reflex?
Parasympathetic fibres from edinger westphal nucleus –> via third cranial nerve –> ciliary ganglion –> via short ciliary nerve –> sphincter pupillae
Sphincter pupillae - which NS?
Dilator pupillae - which NS?
SP - Parasympathetic
DP - Sympathetic
What is the difference in structure and nerve supply of sphincter pupillae and dilator pupillae?
structure : SP spherical, DP radial
nervous: SP supplied by short ciliary nerves
nervous: DP supplied by long ciliary nerves
What is the pathway from the Edinger Westphal nucleus to the Sphincter pupillae (the parasympethetic pathway)?
Edinger westphal –> third cranial nerve through cavernous sinus –> third CN splits into superior and inferior divisions –> inferior division supplies IR, IO, MR and synapses with ciliary ganglion. Post-ganglionic fibres (posterior short ciliary nerves) pierce sclera and enter eyeball and supply ciliary muscle (95%) and sphincter pupillae (5%)
What is the pathway of the sympathetic nerve supply of the pupil?
1) hypothalamic centre causes inhibition of edinger westphal nucleus
2) hypothalamic centre sends nerves to spinal centre of budge (C8, T1, T2, T3, T4) –> leave through sympathetic cervical chain to the superior cervical ganglion (SCG)
3) Post ganglionic fibres from SCG enter skull and coil around the internal carotid artery (carotid plexus) into the cavernous sinus
4) sympathetic fibres pass over the trigeminal ganglion and pass into V1 in cavernous sinus.
5) V1 subdivides into lacrimal branch, frontal branch, nasociliary branch –> long ciliary nerve.
6) long ciliary nerves pierce sclera and supply dilator pupillae to cause dilatation of pupil
what are the functions of the RPE
What is the structure of rod cones from RPE to vitreous?
Outer segment (transductive) –> inner segment (region for maintenance of cellular homeostasis) –> nuclear region (outer nuclear layers) –> transmissive region (outer plexiform/synaptic layer)
Which types of cells are present in the inner nuclear layer? (3)
(1) bipolar neurons
(2) horizontal cells
(3) amacrine cells
What is the difference between the outer segments of rods and cones ? (2)
RODS: cylindrical and contain rhodopsin pigment, made up of vitamin A (night blindness)
CONES: conical and contain iodopsin pigment (colour blindness)
What is the difference in numbers between rods and cones?
rods: 120 million
cones: 5 million
what is the maximum spectral sensitivity of the rod cells?
496nm