Eye and Ear Flashcards
Conjunctivitis Newborn Incidence (5)
- Newborn Incidence is 1.5-12%
- Vertical transmission from mom to baby - Usually will occur within first 28 days of life
- Ophthalmia neonatorum
- Vertical transmission
- Gonorrhea and Chlamydia
Conjunctivitis in Infants- School Age
Twice as likely to be bacterial
Conjunctivitis in School Age and Older
Likely to be viral
Conjunctivitis Pathology (5)
- The surface tissues of the eye and the ocular adnexa are colonized by normal flora such as streptococci, staphylococci
- The primary defense against infection is the epithelial layer covering the conjunctiva.
- Disruption of this barrier can lead to infection.
- Rubbing eye, etc.
- Little children’s hands go all over the place and then touch eye - Secondary defenses include hematologic immune mechanisms carried by the conjunctival vasculature; tear film immunoglobulins and lysozyme; and the rinsing action of lacrimation and blinking.
- Any alteration in this defense allows the bacteria to get through and leads to the clinical presentation of conjunctivitis
- Alterations in the host defense or in the species of bacteria can lead to clinical infection.
- External contamination: contact lens wear, swimming
- Spread from adjacent infections: rubbing of the eyes
Bacterial Conjunctivitis Incidence (2)
- 50-75% of acute infectious conjunctivitis → suppurative, non-neonatal infections (it’s not maternal/vertical transmission)
- 50-75% of infectious conjunctivitis is bacterial
Common Bacterial Conjunctivitis Pathogens (5)
- Haemophilus (decreased with Hib immunization)
- Streptococcus pneumoniae (Most common)
- Staphylococcus aureus ( also most common)
- Moraxella catarrhalis
- Pseudomonas
Bacterial Conjunctivitis Clinical Presentations
Caps lock = main manifestations
- Unilateral or bilateral CONJUNCTIVAL HYPEREMIA
- Mild to moderate PURULENT DISCHARGE
- EARLY MORNING CRUSTING – A BIG ONE!
- Wake up in the morning or from nap and their eyes are stuck together; have to pry the eyelashes apart or use a warm compress; more indicative of bacterial than viral - Red eyes
- Eyelid edema
- Erythema surrounding the eye
- Excessive tearing
- Tearing usually more common with viral, but the patient may feel like they have something in their eye continually - Itching
- PAPILLAE: Vascular reaction – red cobblestone appearance when flipping lid over (do thorough eye exam)
Bacterial Conjunctivitis vs. Cellulitis
With bacterial conjunctivitis, watch for cellulitis – very erythematous
*Abnormal ocular movements, loss of visual acuity, may signal spread of infection beyond the orbital septum (orbital cellulitis)
Bacterial Conjunctivitis: When to stay out of daycare
Any time discharge is present!
Bacterial Conjunctivitis Diagnosis (3)
- Clinical suspicion
- Gram stain and culture if severe
- Refer to ophthalmologist if not resolving
Bacterial Conjunctivitis Management (7)
- Culture NOT usually required outside of the neonatal period because it is a self limiting disease
- Chest X-ray in neonates to rule out pneumonia with conjunctivitis and respiratory symptoms
- No school until discharge has resolved
- If persists > 7-10 days - culture!
- Hygiene
- For Staph etiology – daily lid cleaning baby shampoo, warm compress
- Do not try to pry the eyes open – can be very painful
General Info about Bacterial Conjunctivitis Treatment (4)
- Topical antibiotics = first line agent
* Shortens time and prevents secondary cases by eradicating the organism - Broad spectrum without culture for routine, mild to moderate conjunctivitis
- Treat - 5-10 day range
- Continue it because improvement will occur within 3 days but it isn’t fully eradicated
- Do it for at least 2 more days until it is cleared; try and do 5-7 days - If not cleared by 10 days, see the patient again
Eye drops for conjunctivitis treatment (2)
- Do not interfere with vision
2. May sting – hard to put in alone
Ointments for conjunctivitis treatment (3)
- Advantage of prolonged contact with ocular surface
- Soothing effect
- Blurs vision
Conjunctivitis treatment for younger vs. older child
- Younger: If you want broad spectrum coverage for mild conjunctivitis in younger child use Erythromycin in ointment form
- If older child → go with a drop, Maybe tobramycin
Polytrim (trimethoprim-and polymixin B sulfate) (4)
- Antibiotic topical therapy for conjunctivitis
- Effective against MRSA
- For > 2 months of age
- 1 drop every 3-4 hours (max 6 doses/24 hours) for 7-10 days
Garamycin/Gentak (gentamicin) (5)
- Antibiotic topical therapy for conjunctivitis
- Effective against MRSA
- Gram negative coverage-Pseudomonas, staph aureus, Strep, H. Influ
- Ointment 0.3%: 0.5 inch ribbon q 8-12h
- Drops 0.3%: 1-2 drops q 4h
Tobrex (tobramycin) (4)
- Antibiotic topical therapy for conjunctivitis
- Ointment -0.5 inch ribbon TID (BID)
- Drops – 1-2 drops every 4 hours (4-5 times/day)
- NOT tobradex routinely – only for severe infections with swelling (Because it contains a steroid)
Vigamox (moxifloxacin) (4)
- Antibiotic topical therapy for conjunctivitis
- It stings!!
- 1 year or older
- 1 drop TID (3 times/day) for 7 days
Aza Site (azithromycin) (4)
- Antibiotic topical therapy for conjunctivitis
- 1 year or older
- Macrolide - 7 day treat
- Easier dosing – 1 drop BID x 2 days…followed by 1 drop DAILY x 5 days
Besifloxacin (Besivance) (4)
- Antibiotic topical therapy for conjunctivitis
- > 1 year of age
- 1 drop to affected eyes TID for 7 days
- 4th generation fluoroquinolone – broad spectrum +/-
Erythromycin (4)
- Antibiotic topical therapy for conjunctivitis
- SAFE for infants
- Ointment only: 0.5 inch ribbon to affected eye BID—QID
- Macrolide
Conjunctivitis Incubation
Contagious period ends when course of antibiotics started OR when symptoms/discharge no longer present
Viral Conjunctivitis (3)
- Common, self-limiting
- ADENOVIRUS most common cause – will see fever, sore throat, respiratory symptoms
- If only presentation is eye and not the above then they can go back to school