Eye Flashcards
Enumerate layers of wall of eye
- Outer fibrous layer (cornea & sclera)
- Middle vascular layer or uvea (choroid, ciliary body, iris)
- Inner nervous layer (retina)
Enumerate chambers of the eye and their contents
- Anterior chamber: between cornea & iris contains aqueous humour
- Poterior chamber between iris, lens and suspensory ligament contains aqueous humor
- Vitreous chamber: behind lens & zonule surrounded by retina, it is occupied by the vitreous body
Enumerate layers of the cornea
- Epithelium (stratified squamous non-keratizoned)
- Bowman’s membrane
- Substantia propria (stroma)
- Descemet’s membrane
- Corneal endothelium
Function of superficial microvilli of corneal epithelium
To help retaining a film of tears between them to keep the cornea wet
Bowman’s membarne is formed of….., its injury leads to…..
TypeI collagen/intercellular substance
Scar formation/corneal opacity
Mention contents of corneal substantia propria
About 60 layers of parallel collagen type I bundles aligned at right angles to each other
Flattened fibroblasts-like cells in between these lamellae called keratocytes
Ground substance reach in proteoglycans
Descemet’s membarne is formed by……
Underlying endothelium
Describe feature of corneal epithelium
Signs of active transcellular endocytosis:
Numerous mitochondria
Pinocytotic vesicles as they absorb excess fluid from stroma keeping it relatively dehydrated and maintaining transparency of cornea
Describe the nutritional supply of cornea
Nutrition from aqueous humor (for center) and limbus vessels for periphery
Oxygen from atmosphere
GR: The cornea is transparent
- It is avascular structure
- Regular arrangement of cells & collagen fibers
- Same refractive index of all its components
- Continuous withdrawal of fluids from stroma through endothelium
Enumerate layers of sclera
Episcleral tissue: fibroelastic CT
Sclera proper formed of dense CT
Inner suprachoroid lamina containing melanocytes and less collagen
Mention the histological characters of limbus
Corneal epithelium becomes thickened and cont with bulbar conjunctiva
Bowman’s capsule abruptly ends and is replaced by subconjuctival CT
Substantia propria becomes irregular and forms sclera proper. At this point canal of Schlemm surrounds the limbus
Descemet’s membarne forms trabecular meshwork that drains into the canal
Endothelium lines these channels and the canal of Schlemm
Stem cells are concentrated at the limbus, they are rapidly dividing cells move into corneal epithelium
GR; Sclera is opaque
Due to irregular arrangement of its fibers
Difference in refractive index of its elements
Mention the parts of choroid
- Choriocapillary layer: has rich microvasculature for nourishment of outer 1/3 of retina
- Bruch’s memrane: It is composed of collagen & elastic fibers, innermost component of choroid
In cross-section ciliary body is triangular bound by…,…..,…..
Sclera, vitreous body, lens & posterior chamber
Describe structure of ciliary body
- Loose CT containing elastic fibers, bv, melanocytes & ciliary muscle
- The two surfaces facing lens and vitreous body are covered with two layers of low columnar cells;
A) outer pigmented layer, cont with pigmented epithelium of retina
B) inner non-pigmented layer, cont with sensory layer of retina
Function of ciliary processes and structural specialization
Basolateral membrane infoldings on both if its epithelium layers for aqueous humor secretion