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How are attributuble risks computed
[(Incidence in population) - (Incidence in unexposed group)]/ (Incidence in population)
The rate of the phenomenon in a population relates to ..
the frequency of cases.
highest rank of study design in the epidemiologist’s tool kit
randomized controlled trial
the proportion of people with the condition who have a positive test result.
sensitivity
The proportion of people without the condition who have a negative test result.
specificity
The proportion of people with a positive test who actually have the condition. OR negative test who don’t have the condition
predictive value
BIOSTATS
- Evaluate methodologies, develop sampling techniques, and coordinate data collection to ensure research questions are properly addressed
- Provide analytical methods and software tools necessary to translate data from studies, surveys and medical testing into useful information for health care professionals
- Offer recommendations for improving processes and operating procedures, and help implement productive changes based on those recommendations
COMMUNITY HEALTH
- Work with other scientists and healthcare professionals to investigate the origin and best treatment of diseases
- Research demographics, analyze data and plan educational programs to prevent future outbreaks of disease and injury
- Provide unbiased, scientific findings to policy makers, health professionals and the public
EMERGENCY MANAGEMENT
- Work with community organizations and law enforcement to predict possible emergency scenarios and plan responses
- Train organization employees in emergency response procedures
Strive to reduce harm and panic amongst populations affected by an emergency
ENVIRONMENTAL HEALTH
- Analyze field data to assess pollution levels in the air, water, and soil, as well as climate trends, animal activity, and other environmental variables
- Present written reports that clarify data findings for co-workers, inter-agency colleagues, policymakers, lawmakers, and the community at large
- Address major and minor environmental problems with sustainable, cost-effective strategies
Paul farmer-
harvard epidemiologist, dead…Rwanda
Nathan wolfe-
virologist
William farr
diseases caused by overcrowding, helped John snow
interventions: behavioural, pharmacological, other interventions
behavioural: promoting healthy living for ex.
pharmacological: Beta-blockers, angiotensin, etc.
interventions: environmental and surgical interventions
infective dose
the amount required to cause infection in susceptible subjects
factors in causation
Predisposing factors- age, sex, genetic traits
Enabling (or disabling) factors- low income, poor nutrition, etc.
Precipitating- exposure to specific disease agent associated with onset of disease
Reinforcing- repeated exposure, environmental conditions and unduly hard work
difficult studies to interpret
cological studies usually rely on data collected for other purposes; data on different exposures and on socioeconomic factors may not be available.
- if wrong conclusions are drawn=ecological fallacy
what was causing lung cancer dramatic increase in the 50s,
linked to?
- tobacco use
- asbestos dust and urban air pollution
AIDS without treatment causes HIV patients to…
(about half) develop AIDS within nine years of infection
- treated with antiretrovirals
enteritis necroticans
reported from meat consumption in papa New Guinea
provide the best information about the causation of disease and the most direct measurement of the risk of developing disease.
- expensive
cohort studies are major undertakings and may
require long periods of follow-up since disease may occur
a long time after exposure.
- The nested case-control design makes cohort studies less expensive. The cases and controls are both chosen from a defined cohort, for which some information on expo- sures and risk factors is already available
external validity
requires quality control of the measurements and judgements about the degree to which the results of a study can be extrapolated.
- beyond people, involving lab
internal validity
the degree to which the results of an observation are correct for the particular group of people being studied.
ethical issues in epidemiology
- informed consent