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Anti-Arrhythmia Drugs > Extra Anti-Arryhthmics > Flashcards

Extra Anti-Arryhthmics Flashcards

1
Q

What do you not give class IV with and why

A

Digoxin
Dofetilide
Simvastatin
Lovastatin

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2
Q

What does Digoxin do

A

Shorten refractory in atrial and ventricular myocardium

Lengthen refractory and lower conduction in AV node

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3
Q

When do you give Digoxin

A

A-fib/flutter with impaired LV function or HF

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4
Q

Direct action of Digoxin

A

AV node blocking

Activate Ach-mediated K currents in atrium

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5
Q

Indirect effects of Digoxin

A

Hyperpol
Shorten atrial AP
Increase AV refractory

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6
Q

Effect of Digoxin toxicity

A

V-tach

V-fib

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7
Q

Which miscellaneous antiarrhythmic is given in IV form

A

Adenosine

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8
Q

What is the DOC for abolishing acute SVT in emergency

A

Adenosine

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9
Q

Which antiarrhythmic is a P1r agonist

A

Adenosine

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10
Q

What does high dose Adenosine do

A

Decrease conduction velocity
Prolong refractory
Decrease AV automaticity

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11
Q

How does Adenosine act

A

Increase K conduction

Decrease Ca influx leading to hyperpol

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12
Q

What are the AE for Adenosine

A

Chest pain similar to MI
Hypotension
Bronchoconstriction in asthmatics

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13
Q

What is a functional Ca antagonist

A

Mg

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14
Q

What is used in bradyarrhythmia to decrease vagal tone and increase HR

A

Atropine

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15
Q

When is Mg used

A 
Torsades de Pointes	
Digitalis arrythmias (also lidocaine)
	Arrhythmia prophylaxis in acute MI
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16
Q

When is Atropine used

A

Bradyarrhythmia

17
Q

What is the most common clinical arrhythmia

A

A-fib

18
Q

What drugs are involved in Rhythm control of A-fib

A

Class IC
Class III
IA (more AE)

19
Q

What drugs are involved in Rate control of A-fib

A

Ca channel blockers
Beta blockers
Digoxin

20
Q

When do you use IV Heparin to control thromboembolic events in A-fib

A

Unstable pts needing immediate cardioconversion

21
Q

When do you use oral Warfarin to control thromboembolic events in A-fib

A

If cardioversion can be delayed 3-4 days

Anti-Arrhythmia Drugs (5 decks)

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