Extra Flashcards
1
Q
What does a raised ESR + osteoporosis suggest?
A
Multiple myeloma
2
Q
What does ciprofloxacin do in G6PD deficiency?
A
Can cause hemolysis
3
Q
How do you diagnose a blood transfusion reaction?
A
Direct coombs test
4
Q
What are mirror image nuclei associated with?
A
Reed-Sternberg cells
5
Q
What is haemochromatosis?
A
Autosomal recessive disorder of iron absorption + metabolism
Causes iron accumulation
Inheritance of mutations on HFE gene on chromosome 6
6
Q
What is the characteristic iron study profile in haemochromatosis?
A
Raised transferrin
Raised ferritin
Low TIBC
7
Q
Dx of haemochromatosis
A
Transferrin saturation increased Raised ferritin + iron Low TIBC Liver biopsy: Perl’s stain Joint x rays show chondrocalcinosis
8
Q
Tx of haemochromatosis
A
Venesection
