Exposure

Question 1

Shock

Answer 1

A critical state of hemodynamic instability reflecting progressive circulatory failure and hypoperfusion of vital organs, resulting in cellular dysfunction and eventual organ failure.

Question 2

Hypoperfusion

Answer 2

A state of decreased blood flow and inability to meet metabolic demands of tissues resulting in cellular dysfunction and tissue death.

Question 3

qSOFA
Definition
Parameters

Answer 3

A quick assessment tool to identify patients with infection (suspected sepsis) at risk of acute deterioration, prolonged ICU admission and/or death.
1. Hypotension - SBP </= 100mHg
2. Tachypnoea - RR >/=22
3. Altered mental state - GCS <15

Question 4

Acute Organ Dysfunction

Answer 4

1. Cardiovascular – SBP <90 or MAP <70mmHg for 60min despite fluid bolus, requires vasopressor support
2. Respiratory – PF ratio < 250, PEEP >7.5cmH20, requires mechanical ventilation
3. Renal – U/O <0.5ml/kg/hr, creatinine 50% > baseline, requiring acute dialysis.
4. Haematological – platelet count <1000000mm3 or elevated PTT 5. Metabolic – pH < 7.3and elevated lactate.
5. Hepatic – liver enzymes >2 x limit
6. CNS – altered LOC/GCS

Question 5

Lactate

Answer 5

Lactate < 2mmol/L

Question 6

WBC

Answer 6

4-12 x 10(9)/L

Question 7

MET Criteria

Answer 7

Clinician concern.