Exploratory Research Flashcards

1
Q

what is exploratory research

A

making comparisons within groups

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2
Q

what are the uses of exploratory research

A

systemic investigation of relationships among two or more variables
commonly used in healthcare to investigate relationship between exposure and disease status

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3
Q

what are the characteristics of exploratory research

A

data collection can be prospective or retrospective, as well as longitudinal or cross-sectional

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4
Q

prospective

A

future
variables measured through direct recording in the present
observations made as variables progress through time

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5
Q

what is the major limitation of prospective studies

A

time consuming

risk for attrition

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6
Q

retrospective

A

past
examination of data previously collected
often obtained via EMR, databases, surveys, etc

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7
Q

major limitation of retrospective studies

A

unable to control variables or quality of data collection

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8
Q

longitudinal design

A

subject followed over time

data collected in time sequence of repeated measurements at prescribed intervals

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9
Q

major advantages of longitudinal design

A

researchers able to describe patterns of change

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10
Q

major disadvantages of longitudinal design

A

huge commitment

attrition easy to see

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11
Q

cross sectional design

A

study of stratified group of subjects at one point in time

compares characteristics/variables in one moment of time

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12
Q

major advantages in cross sectional design

A

much more efficient design

not as threatened by testing effects

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13
Q

major disadvantages in cross sectional design

A

can be difficult to discern if results are effects of age or passing of time vs effects of extraneous sampling variables

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14
Q

longitudinal prospective research

A

follow same subjects over a period of time

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15
Q

longitudinal retrospective research

A

look at a period of time over data that was already collected

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16
Q

cross sectional prospective research

A

one slice of time in a bigger data set

17
Q

cross sectional retrospective research

A

one point in time in the past

18
Q

types of exploratory research

A

cohort

case control

19
Q

cohort study

A

researcher selects subjects without outcome of interest and monitor if outcome develops over time

20
Q

is a cohort study prospective or retrospective

A

prospective

21
Q

is a cohort study exploratory or explanatory

A

can be both

22
Q

major advantages of a cohort study

A

able to identify temporal sequence between exposure to risk factors and development of outcome
>1 disorder can be evaluated

*framingham heart study

23
Q

major disadvantages of a cohort study

A

less useful for rare disorders

prone to attrition

24
Q

case control study

A

aims to determine if frequency of exposure to certain variable varies between those with and without disease

case: has disease
control: no disease

25
Q

is a case control study prospective or retrospective

A

retrospective

26
Q

major advantages of a case control study

A

helpful for determining prognosis-centered research questions

easy to collect data

especially helpful for analyzing disorders with long latency periods and rare disorders

27
Q

major disadvantages of a case control study

A

difficult to gauge temporal relationships

bias: selection and/or observation bias, risk for misclassification