Excretion of meds in human milk

Question 1

% of infants breastfeeding when discharged

% of infants breastfeeding after 6 months

Answer 1

77; 35

Question 2

Advantages of breast milk

Answer 2

passive transfer of antibodies
dec UTI, otitis media, GI illness
enhanced bonding etc

Question 3

Who takes more meds, preg or lactating moms:

Answer 3

lactating

Question 4

pH of breastmilk

Answer 4

7.0

Question 5

Make up of breastmilk

Answer 5

fat and protein in a lactose and mineral solution

Question 6

How many mL’s can a lactating mother produce in a day?

Answer 6

600 mL

Question 7

Rate of milk synthesis is at its maximum when breast is:

Answer 7

empty

Question 8

The mechanism of drug excretion is through

Answer 8

diffusion

degree of ionization of drug and a difference in pH exists across the membranes

Question 9

Drugs and chemicals <_____ daltons can cross by simple diffusion

Answer 9

200

Question 10

Concentrations in milk parallel the plasma concentrations in

Answer 10

urine

Question 11

transport from plasma to milk is ____

Answer 11

rapid

Question 12

Amount of drug available for the infant to absorb is <___% of maternal dose

Answer 12

1

Question 13

risk to infant is very small with the exception of the neonate and infant younger than:

Answer 13

2 months of age

Question 14

use of these substances in common and may need to delay the test, use a different test, or dc breastfeeding for set periods of time

Answer 14

radioactive isotopes

Question 15

Most common herbal supplement in lactating mothers

Answer 15

fenugreek

Question 16

Can possible decrease milk production

Answer 16

oral contraceptives

Question 17

These drugs include antidepressants, anti anxiety, and antipsychotic drugs

Answer 17

psychotropic drugs

Question 18

psychotropic drug milk/plasma ratio usually:

Answer 18

<1

Question 19

Short and long term affects of psychotropic drugs

Answer 19

short: none
long: unknown