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Phm 540 > Excipients > Flashcards

Excipients Flashcards

1
Q

EDTA (ethylene diamine tetra acetic acid)

A

chelator, penetrator

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2
Q

magnesium stearate

A

lubricant (insoluble in H2O)

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3
Q

corn starch

A

binder, disintegrant

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4
Q

colloidal silicon dioxide

A

glider (improves flow), dessicant (absorbs moisture)

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5
Q

gelatin

A

binder (makes capsules and caps shells)

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6
Q

talc

A

lubricant (not as good as mag stearate)

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7
Q

sucrose

A

sweetener, diluent, filler

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8
Q

calcium stearate

A

lubricant (insoluble in H2O)

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9
Q

stearic acid

A

lubricant (more soluble in H2O), emulsifier

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10
Q

titanium dioxide

A

white pigment (insoluble in H2O)

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11
Q

HPMC

A

gelatin alternative for caps, used in controlled release

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12
Q

sodium lauryl sulfate

A

surfactant, lubricant (water-soluble)

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13
Q

PVP/Povidone

A

binder, makes water-soluble matrices

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14
Q

croscarmellose sodium

A

super disintegrant

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15
Q

propyl paraben

A

preservative

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16
Q

benzalkonium bromide

A

preservative (NEVER use in children –> cause death)

17
Q

xanthum gum

A

binder, thickening agent, alternative for gelatin in emulsions/suspensions

18
Q

sodium saccharin

A

sweetener

19
Q

sucralose

A

sweetener

20
Q

sorbitol

A

plasticizer, sugar-alternative

higher conc –> laxative, osmotic agent

21
Q

ferric oxide

A

red dye

22
Q

microcrystalline cellulose

A

tablet diluent (best for direct compression)

23
Q

dicalcium phosphate

A

tablet filler (insoluble in water, can trap drug particles and slow down drug release)

24
Q

sodium starch glycolate

A

super disintegrant

25
Q

methyl paraben

A

preservative

26
Q

sodium benzoate

A

preservative

27
Q

potassium sorbate

A

preservative

28
Q

carbomer

A

gelling agent, suspending agent

29
Q

aspartame

A

sweetener

30
Q

mannitol

A

sweetener (highly soluble, can use as alternative to microcrystalline cellulose)

31
Q

Tween 80/ Polysorbate 80

A

emulsifier, surfactant

32
Q

sodium bicarbonate

A

alkalizing agent (change pH to be more basic – esp in stomach)

Phm 540 (4 decks)

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