exchange of substances Flashcards

1
Q

what is the equation for diffusion rate?

A

SA x conc. gradient/ diffusion pathway

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2
Q

how can you maximise diffusion rate using the equation?

A

1) maximise SA and conc. gradient
2) minimise diffusion pathway

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3
Q

why and how are fish adapted for gas exchange? (6)

A

1) need a specialised gas exchange surface as they have a small SA:V ratio
2) along each gill arch there are multiple gill filaments which are lined with gill lamellae (where gas exchange occurs)- this provides a large SA
4) blood and water flow across the lamellae in a counter current direction meaning they flow in the opposite direction to one another
5) this ensures that a steep diffusion gradient is maintained so that the maximum amount of oxygen is diffusing into the deoxygenated blood from the water
6) short diffusion pathway as gas exchange only happens on gill lamellae which are very thin

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4
Q

what is the counter-current principle?

A

1) blood and water flow across the lamellae low in the opposite direction to one another
2) this ensures that a steep diffusion gradient is maintained across the entire width of the gill lamellae so that the maximum amount of oxygen is diffusing into the deoxygenated blood from the water
3) ensures equilibrium is not reached

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5
Q

why does the volume of water passing over the gills increase if the temperature of the water increases?

A

At higher temperatures, less oxygen dissolves in the water so fish need to respire faster by absorbing more oxygen from the water

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6
Q

why is counter current flow useful to a fish? (2)

A

1) higher rate of oxygen uptake for respiration so faster respiration rate
2) faster swimming speed

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7
Q

what is the relationship between the size of an organism and
its surface area to volume ratio? (2)

A

1) as the size of an organism increases, its surface area to volume ratio decreases.
2) because its volume increases faster than its surface area, meaning the no. of cells respiring and using the O2 becomes greater than that of the area available to diffuse O2

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8
Q

what is the physiological significance of surface area to volume ratio? (3)

A

1) small organisms with a higher SA:V lose heat energy more quickly per kg of bodyweight
2) so they have to respire fast to replace the body heat they are losing
3) large organisms with a lower SA:V have specialised gas exchange surfaces (gills, lungs, leaves) to increase the surface area for O2 diffusion/

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9
Q

what adaptations do single-celled organisms have for gas exchange? (4)

A

1) small and have a large SA:V ratio
2) oxygen is absorbed by diffusion across their body surface which is only covered by a cell-surface membrane
3) Carbon dioxide from respiration diffuses out across their body surface
4) if organism has a cell wall, it doesn’t act as an additional barrier to the diffusion of gases

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10
Q

what adaptations do insects have for gas exchange? (5)

A

1) tracheal system made up of tracheae which branch out to form additional tracheoles which increase surface area.
2) large number of tracheoles which have thin walls so there is a short diffusion distance to cells
3) O2 and CO2 conc. gradient is maintained by body movement and muscle contraction which moves air
4) tracheae provide tubes full of air so fast diffusion into insect tissues
5) fluid in the ends of the tracheoles moves out into tissues during exercise so faster diffusion through the air to the gas exchange surface

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11
Q

how does the production of lactic acid during exercise speed up oxygen diffusion in insects? (3)

A

1) ends of the tracheoles are filled with water- during intense activity, muscles around the tracheoles carry out anaerobic respiration producing lactic acid.
2) This lowers the water potential of muscle cells so water moves into them from the tracheoles by osmosis
3) The volume of water in the ends of the tracheoles decreases and in doing so draws air further into them, speeding up diffusion of oxygen.

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12
Q

what is the function of spiracles in insects? (2)

A

1) gases enter and leave the tracheae via spiracles which can open and close by a valve
2) periodically open to allow gas exchange

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13
Q

how are the leaves of dicotyledonous plants adapted for gas exchange? (4)

A

1) large number of stomata which allow gas exchange found in the leaf’s bottom surface means no cell is far from the stomata, reducing the diffusion distance.
2) air spaces in the spongy mesophyll tissue provide a large surface area to allow gases to enter and move around the leaf and easily come into contact with photosynthesising mesophyll cells
3) CO2 concentration gradient is maintained from the air to the leaf cells as there is a low conc at the palisade cells due to it being used in photosynthesis
4) short diffusion pathway is also provided through the thin flat surface of the leaf

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14
Q

what are the structural and functional compromises between the opposing needs for efficient gas exchange and the limitation of water loss shown by terrestrial insects? (3)

A

1) gas exchange causes water loss because when spiracles open to allow gas exchange, water evaporates out
2) If insects are losing too much water, they close their spiracles using muscles.
3) insects have a waterproof, waxy cuticle all over their body and tiny hairs around their spiracles, both of which reduce evaporation.

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15
Q

what are structural and functional compromises between the opposing needs for efficient gas exchange and the limitation of water loss shown by xerophytic plants? (5)

A

1) for optimal growth stomata would stay open at all times to allow maximum gas exchange so maximum rate of carbon dioxide uptake and maximum rate of photosynthesis however gas exchange causes water loss because when stomata open to allow gas exchange, water evaporates out
2) however as well as allowing gas exchange, stomata will also allow water loss. This must be minimised therefore stomata close under low light conditions (when less carbon dioxide is required for photosynthesis)
3) plant stomata open in day to allow gas exchange
4) waxy cuticle reduces evaporation
5) Xerophytes -> plants specially adapted to living in dry conditions (e.g. cacti and marram grass)

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16
Q

how does gas exchange in leaves occur? (3)

A

1) carbon dioxide/oxygen diffuse through the stomata, which are opened by guard cells becoming turgid
2) carbon dioxide/oxygen diffuse into mesophyll layer into air spaces
3) carbon dioxide/oxygen then diffuse down a concentration gradient.

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17
Q

how do stomata open?

A

1) guard cells absorb water by osmosis and becomes turgid
2) causes stomata to open during the day to allow diffusion of CO2

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18
Q

how do stomata close?

A

1) guard cells lose water by osmosis and becomes flaccid
2) causes stomata to close at night as no photosynthesis is happening

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19
Q

why is there a net CO2 uptake during the day? (3)

A

1) photosynthesis rate is higher than respiration rate
2) more CO2 is used for photosynthesis than is made by respiration
3) CO2 diffuses in through open stomata

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20
Q

in plants why is there a net uptake of O2 at night? (3)

A

1) respiration rate is higher than photosynthesis rate/ photosynthesis is not occurring
2) more O2 is being used for respiration than is being made by photosynthesis
3) O2 diffuses in through closed stomata

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21
Q

what is the ‘compensation point’ in photosynthesis? (2)

A

1) photosynthesis and respiration rates are equal
2) all CO2 made by respiration is used for photosynthesis

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22
Q

why are the stomata usually open in the daytime and closed at night? (3)

A

1) allow CO2 to diffuse in for photosynthesis
2) closed at night to prevent loss of water through evaporation/transpiration
3) no photosynthesis occurs at night

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23
Q

why would a herbicide that closes the plant’s stomata cause the death of that plant? (3)

A

1) CO2 cannot diffuse in through stomata
2) less photosynthesis will happen
3) no glucose/sugars produce so plant will die

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24
Q

describe the similarities and differences between plant leaves and insect tracheal system as gas exchange systems (5)

A

1) both have a large surface area (air spaces in the spongy mesophyll layer and lots of branched tracheoles)
2) both have a short diffusion pathway as insects are small and thin tracheole walls and leaves are thin and flat.
3) both have pores to allow gas exchange (stomata and spiracles) which can be closed to reduce water loss through evaporation
4) insects have the ability to ventilate trachea by contracting muscles whereas leaves cannot
5) they differ in which gases diffuse in and out. During the day, CO2 diffuses into the leaves and O2 diffuses out. Whereas in insects, O2 diffuses in and CO2 diffuses out.

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25
explain how young fish get enough oxygen to their cells without having gills (2)
1) diffusion across body surface/skin 2) short diffusion pathway/ large SA:V ratio
26
what is an organ?
a group of tissues which which work together to perform a specific function
27
what is the advantage of having a one-way flow of water over gills? (2)
1) less energy needed 2) continuous flow of water/ O2
28
outline the gross structure of the human gas exchange system and describe how air moves when we inhale (6)
1) trachea- lined with C-shaped cartilage to keep to open 2) bronchi- 2 branches which extend from trachea 3) bronchioles- highly branched narrow tubes which extend from bronchi 4) alveoli-tiny air sacs found on the ends of bronchioles which give a large surface area 5) lungs- act as a specialised exchange surface which humans need as we have a small SA:V ratio and fast metabolic rate. 6) when breathing air travels from the mouth, down the trachea, bronchi and bronchioles down a pressure gradient, before arriving in the alveoli which is the site of gas exchange
29
describe the mechanism of breathing when humans inhale (6)
1) external intercostal muscles contract to lift the ribcage upwards and outwards 2) internal intercostal muscles relax due to the antagonistic interaction between external and internal intercostal muscles 3) diaphragm muscle contracts and becomes and flatter 4) this increases the volume of the lungs and thorax 5) so decreases pressure in the lungs 6) air moves into the lungs from a higher pressure to a lower pressure down a concentration gradient
30
describe the mechanism of breathing when humans exhale (6)
1) external intercostal muscles relax allowing the ribcage to fall due to gravity 2) diaphragm relaxes and returns to its dome shape 3) this decreases the volume of the lungs and thorax 4) so increases pressure in the lungs 5) air moves out of the lungs from a higher to lower pressure 6) this mechanism is helped by the elastic recoil of the alveoli which raises the alveolar pressure to push air out
31
describe the mechanism of breathing when humans undergo forced expiration (5)
1) same process a regular expiration 2) internal intercostal muscles contract to actively pull ribs downwards 3) decreases the volume of the thorax and lungs more quickly 4) pressure in the lungs rises more quickly so there is a greater pressure gradient 5) air moves out of the lungs more quickly
32
describe the diffusion of oxygen through the alveolar epithelium
during gas exchange oxygen diffuses from the alveolus cavity across the alveolar epithelium and capillary endothelium into the blood, travelling down a diffusion gradient, whilst carbon dioxide diffuses in the opposite direction
33
what are the essential features of the alveolar epithelium as a surface over which gas exchange takes place (5)
1) alveolar epithelium is thin/one cell thick and thin capillary endothelial cells create a short diffusion pathway 2) millions of tiny create a large surface area for gas exchange 3) each alveolus is surrounded by a network of capillaries to remove exchanged gases and therefore maintains a large concentration gradient 4) this is achieved by ventilating the lungs to maintain air with a high oxygen concentration in the alveoli and exhaling poor air. Blood flow through capillaries also ensures that deoxygenated blood is brought to the capillaries around the alveoli 5) blood flow through capillaries is also slow, to allow time for more oxygen to diffuse
34
how do you calculate breathing rate from a graph?
60 sec/ time for 1 breath (work this out using the graph)
35
what is tidal volume?
volume breathed in during 1 breath
36
how do you calculate pulmonary ventilation rate?
tidal volume x breathing rate
37
during exercise, what 2 factors could cause the pulmonary ventilation rate to increase? why is this necessary? (3)
1) increase tidal volume 2) increase breathing rate 3) to diffuse more oxygen for respiration
38
how can you work out inspiration is occurring from a graph? (2)
1) lung volume increases 2) lung pressure is below 0/ below atmospheric pressure
39
how can you work out expiration is occurring from a graph? (2)
1) lung volume decreases 2) lung pressure is above 0/ above atmospheric pressure
40
pulmonary fibrosis causes thickening of the alveoli epithelial issue and the loss of recoil of the alveoli, explain how this causes a lack of oxygen in an infected person's blood (3)
1) slower diffusion of oxygen into the person's blood 2) thicker epithelial cells means there's a longer diffusion pathway 3) lack of elastic recoil makes expiration of deoxygenated air less effective, reducing the concentration gradient of oxygen.
41
what happens during digestion?
large biological molecules are hydrolysed to smaller molecules that can be absorbed across cell membranes.
42
outline the digestion of carbohydrates by amylases and membrane-bound disaccharidases (5)
1) carbohydrates are hydrolysed by carbohydrases into monosaccharides 2) starch digestion begins in the mouth where salivary amylase hydrolyses the glycosidic bonds in the starch to form the disaccharide maltose 3) salivary amylase is denatured by the low pH of stomach acid 4) pancreatic amylase continues this hydrolysis in the small intestine 5) the glycosidic bond in maltose is then hydrolysed by maltase, a membrane bound disaccharidase, to form a-glucose
43
where is maltase found?
part of the cell-surface membranes of the epithelial cells that line the small intestine
44
outline the digestion of lipids by lipase, including the action of bile salts (4)
1) lipids are hydrolysed by lipases to form glycerol and fatty acids 2) before this happens, emulsification of the lipids occurs 3) emulsification describes when lipids are firstly split up into tiny droplets called micelles by bile salts which are produced by the liver 4) this is important as it increases the surface area of the lipids so lipase digestion is speeded up
45
outline the digestion of proteins by endopeptidases, exopeptidases and membrane-bound dipeptidases (5)
1) proteins are hydrolysed by proteases into amino acids 2) in stage 1, endopeptidases only hydrolyse the 'internal' peptide bonds in the polypeptides due to the shape of its active site, forming di and tri peptides 3) this increases substrate concentration for exo/ dipeptidases 4) in stage 2, the di & tri peptides are hydrolysed into amino acids by exopeptidases and dipeptidases. 5) these only hydrolyse the 'terminal' peptide bond
46
outline the human digestive system (6)
1) Glands - the salivary glands and glands in the pancreas produce digestive juices/enzymes 2) oesophagus- muscles squeeze food along 3) The stomach and small intestine - the sites of digestion 4) The liver - produces bile 5) Small intestine - the site of absorption and digestion through hydrolysis 6) Large intestine - site of water reabsorption
47
outline the mechanisms for the absorption of glucose by cells lining the ileum (4)
1) the absorption of monosaccharides such as glucose use the mechanism of co-transport 2) sodium ions and glucose molecules are co-transported into the epithelial cells via facilitated diffusion 3) the glucose molecules diffuse across the epithelial cell and enter the capillary at the other end of the cell by facilitated diffusion using a glucose carrier protein 4) the concentration gradient of sodium ions is maintained by the active transport of sodium ions out of the cell and into the blood via a sodium-potassium pump at the other end of the cell
48
outline the mechanisms for the absorption of amino acids by cells lining the ileum (4)
1) the absorption of amino acids uses the mechanism of co-transport 2) sodium/potassium pump uses ATP to actively transport sodium out of the cell and create a low conc. od sodium in the cell 3) sodium and an amino acid are co transported bringing a sodium down its conc gradient and an amino acid against its conc gradient, from the intestine into the epithelial cell 4) amino acid carrier protein allows facilitated diffusion of the amino acid
49
outline the mechanisms for the absorption of lipids by cells lining the ileum and the role of micelles (8)
1) in the intestines, monoglycerides and fatty acids associate with bile salts to form micelles which are small spheres/droplets 2) monoglycerides and fatty acids are not very soluble so the micelles aid the transport of these molecules to the surface of the epithelial cells 3) micelles break down when they come into contact with the epithelial cells lining the ileum, releasing the monoglycerides and fatty acids 4) fatty acids and monoglycerides are non polar so do simple diffusion across the epithelial cell membrane and are transported to the SER 5) at the SER the fatty acids and monoglcyerides are recombined to form triglycerides 6) triglcyerides combine with lipoproteins and cholesterol to form chylomicrons 7) chylomicrons leave the cell via exocytosis of small vesicles 8) lymph and blood vessels transport chylomicrons to endothelial cells which rehydrolyse the triglycerides into fatty acids and glycerol for storage or respiration
50
why is the left ventricle wall thicker than the right ventricle wall? (2)
1) there is more muscle which is required to contract with more force and generate a higher pressure 2) this allows it to pump blood around the body and to the kidney, which requires high pressure blood for ultrafiltration
51
explain the importance of the atrioventricular valves between the atria and ventricles (2)
1) atrioventricular valves close when ventricle pressure is greater than atrial pressure 2) to stop blood flowing backwards from the ventricles to atria
52
explain the importance of valve/heart tendons (2)
1) heart/valve tendons stop atrioventricular valves from inverting 2) allowing them to work correctly to prevent blood from flowing backwards from ventricles to atria
53
what is stage 1 of the cardiac cycle? (4)
1) atrial systole (typically 0.1 sec) 2) atria contract so their pressure rises 3) this opens the atrioventricular valves as atrial pressure is greater than ventricle pressure 4) so blood flows from the atria to the ventricles
54
what is stage 2 of the cardiac cycle? (5)
1) ventricular systole (typically 0.2 sec) 2) ventricles contract so their pressure rises 3) this opens the semi-lunar valves as ventricle pressure is greater than artery pressure 4) so blood flows from the ventricles into the arteries 5) atrioventricular valves close because ventricle pressure is greater than atrial pressure, so prevents blood from flowing backwards
55
how can you identify ventricular systole from a diagram? (2)
1) semi-lunar valves will be open as ventricle pressure is > than artery pressure 2) atrioventricular valves will be closed as ventricle pressure is > than atrial pressure so prevents blood from flowing backwards
56
how can you identify atrial systole from a diagram? (2)
1) atrioventricular valves will be open as atrial pressure is greater than ventricle pressure 2) atria are contracting which may be indicated by arrows
57
what is stage 3 of the cardiac cycle? (4)
1) diastole (typically 0.5 sec) 2) heart relaxes and atria fill will blood 3) blood trickles through open atrioventricular valves into the ventricles 4) semi-lunar valves are closed because artery pressure is greater than ventricle pressure, so prevents blood from flowing backwards from the arteries into the ventricles
58
how do you calculate the length of 1 cardiac cycle?
60/ heart rate
59
what is cardiac output?
volume of blood pumped out per minute
60
how do you calculate cardiac output?
heart rate (bpm) x stroke volume (vol pumped in 1 beat)
61
exam Q: a student investigated the effect of changing surface area on the rate of diffusion of a solution into the centre if agar blocks state 5 variables the student controlled in order to obtain valid results (5)
1) temperature 2) conc. of indicator 3) pH of solution 4) type of agar 5) ensure total surface area of the block is in contact with the solution/acid/
62
exam Q: describe how gas exchange occurs in single-celled organisms and explain why this method cannot be used by large, multicellular organisms (3)
1) diffusion across cell surface membrane 2) large organisms have a smaller sa: vol ratio 3) diffusion pathway would be too long/ too slow for large organisms
63
exam Q: describe how the structure of the insect gas exchange system: - provides cells with sufficient oxygen - limits water loss (5)
1) insect gas exchange system consists of spiracles, tracheae and tracheoles 2) spiracles allow diffusion of O2 into the insect 3) tracheoles are highly branched so large surface area for gas exchange 4) tracheole walls are thin so short diffusion pathway 5) tracheole walls are permeable to oxygen 6) spiracles can close so no water loss 7) hairs around spiracles reduce water loss
64
exam Q: describe how humans breathe in and out (5)
breathing in: 1) diaphragm contracts and flattens 2) external intercostal muscles contract and ribcage is pulled up and out 3) volume increases and pressure deceases in the lungs and thorax breathing out: 4) diaphragm relaxes and returns to dome shape 5) external intercostal muscles relax and ribcage moves down and in 6) volume decreases and pressure increase in the lungs and thorax
65
exam Q: explain why death of alveolar epithelium cells reduces gas exchange in human lungs (3)
1) reduced surface area 2) increased distance for diffusion 3) reduced rate of gas exchange
66
exam Q: to observe the fish gills, 2 stains must be used, the first stain binds to DNA, the second stain binds to the red blood cells explain why a second stain would be needed to stain the red blood cells
red blood cells do not have a nucleus/ DNA
67
exam Q: the damage to the gills causes uncontrolled cell division in the cells around the capillaries in the gill filaments. Other than SA:V, describe one way this uncontrolled cell division changes the gills and how this difference would affect gas exchange (3)
1) more cells so wider/thicker gill filament 2) longer diffusion pathway 3) so slower gas exchange/ rate of diffusion
68
exam Q: describe and explain one feature of the alveolar epithelium that makes the epithelium well adapted as a surface for gas exchange. Do not refer to surface area or moisture in your answer. (2)
1) flattened cells/ single layer of cells/ one cell thick 2) reduces diffusion pathway OR 3) permeable 4) allows diffusion of oxygen/ CO2
69
exam Q: tidal volume is the volume of air inhaled and exhaled during a single breath when a person is resting. The tidal volume in a person with emphysema is reduced compared with the tidal volume in a healthy person. Suggest and explain how a reduced tidal volume affects the exchange of carbon dioxide between the blood and alveoli (3)
1) less carbon dioxide exhaled/ moves out of the lung/ more carbon dioxide remains in the lung 2) so reduced diffusion/ concentration gradient between blood and alveoli 3) so less/slower movement of carbon dioxide out of the blood/ more carbon dioxide stays in the blood
70
how do heart valves/ valve tendons help to maintain the flow of blood in one direction through the heart? (2)
1) stop valves from inverting 2) prevents blood from flowing backward from ventricles to atrium
71
describe the processes involved in the absorption and transport of digested lipid molecules from the ileum into lymph vessels (5)
1) micelles contain bile slats, monoglcyerides and fatty acids 2) they release these fatty acids and monoglycerides into the cells lining the ileum 3) fatty acids/monoglycerides are then absorbed by diffusion into the cell 4) triglycerides reformed in cells 5) vesicles move to cell membrane/ exocytosis
72
describe the role of micelles in the absorption of fats into the cells lining the ileum (3)
1) micelles include bile salts and fatty acids 2) release fatty acids to cells lining the ileum 3) fatty acids absorbed by diffusion
73
describe the role of enzymes in the digestion of proteins in a mammal (4)
1) hydrolysis of peptide bonds 2) endopeptidase act in the middle of polypeptide 3) exopeptidases act at end of protein/polypeptide 4) dipeptidase acts on dipeptide/between two amino acids/ dipeptidase produces single amino acids
74
Explain the advantages of lipid droplet and micelle formation (3)
1) droplets increase surface areas (for lipase action) 2) So faster hydrolysis / digestion (of triglycerides / lipids) 3) Micelles carry fatty acids and glycerol / monoglycerides through membrane / to (intestinal epithelial) cell
75
how is the Golgi apparatus involved in the absorption of lipids (3)
1) modifies/processes triglycerides 2) combines triglycerides with proteins 3) packaged for release/exocytosis so forms vesicles
76
Cells lining the ileum of mammals absorb the monosaccharide glucose by co-transport with sodium ions. Explain how (3)
1) sodium ions actively transported from ileum cell to blood; Golgi (apparatus); 2) maintains / forms diffusion gradient for sodium to enter cells from gut (and with it, glucose); 3) glucose enters by facilitated diffusion with sodium ions;
77
what is the general pattern of blood circulation in a mammal? (Names are required only of the coronary arteries and of the blood vessels entering and leaving the heart, lungs and kidneys). (10)
1) mammals have a double circulatory system 2) blood passes through the heart twice on a complete circuit of the body 3) oxygenated blood leaves the heart through the aorta to the rest of the body 4) oxygen is diffused to respiring tissue 5) deoxygenated blood enters the heart through the vena cava 6) blood leaves to go to the lungs via the pulmonary artery 7) blood becomes oxygenated at the lungs 8) oxygenated blood then enters the heart through the pulmonary vein, ready to be pumped out via the aorta 9) the renal artery takes blood to the kidneys where it leaves by the retail vein 10) the coronary arteries take oxygenated blood to heart cells
78
what is the structure of arterioles related to its function? (3)
1) extra muscle layer that contracts- causes constriction of the arteriole 2) muscle relaxation causes dilation of the arterioles 3) allow blood flow to organs to be reduced/increased according to need
79
what is the structure of arteries related to its function? (4)
1) thick elastic layer that stretches and recoils with each surge of blood to even out the flow 2) thick muscle layer to ensure arteries don't burst under high pressure 3) carry high pressure, usually oxygenated blood, away from the heart 4) no valves needed, except those immediately next to the ventricles, as blood is under high pressure
80
what is the structure of capillaries related to its function? (4)
1) very narrow lumen causing red blood cells to squeeze through- reduced diffusion pathway 2) many, many capillaries increase the surface area for faster diffusion 3) minimal diffusion pathway from blood to tissue fluid 4) vessel wall is a single layer of endothelial cells, with increased permeability
81
what is the structure of veins related to its function? (4)
1) large lumen reduces overall friction to aid blood flow back to the heart 2) thin muscle layer and thin elastic layer as the blood is at low pressure, with little risk of bursting vein 3) valves present to prevent back flow of low pressure blood 4) veins are compressed by major leg muscles to help blood flow against gravity