Exchange (Chapter 6) Flashcards
How are epithelial cells adapted for absorption?
Microvilli give large SA
Many mitochondria - release energy for active transport
Carrier proteins - for active transport & facilitated diffusion
Co-Transport of sodium ions and glucose
Membrane bound enzymes digest disaccharides and produce glucose.
Define Digestion
The hydrolysis of larger/insoluble molecules into smaller, soluble ones.
Where is amylase made?
Salivary glands, pancreas and small intestine
What does amylase hydrolyse and what to?
Starch > Maltose
Where is maltase made?
Epithelial lining of small intestine
What does maltase hydrolyse and what to?
Maltose > 2 alpha glucose
Describe the active transport of glucose
Transported by co-transport as 2 molecules are needed.
1) Sodium ions are actively transported to blood from epithelial cells by Na/K pump.
2) Forms diffusion gradient for sodium to enter from lumen.
3) Glucose enters by facilitated diffusion.
Describe the Digestion of Proteins
1) Hydrolysis of peptide bonds.
2) Endopeptidases hydrolyse internal peptide bonds from polypeptides to smaller peptide chains (more ends for exopeptidases).
3) Exopeptidases remove terminal amino acids.
4) Dipeptidases hydrolyse dipeptides into amino acids.
Describe the Digestion of Lipids
1) Lipids are split up into smaller droplets by bile salts).
2) Droplets increase surface area (for lipase/ensyme action).
3) Faster hydrolysis/digestion of lipids/triglycerides
4) Micelles carry fatty acids and glycerol/monoglycerides to/through membrane to internal epithelial cells.
5) Fatty acids and glycerol enter the intestinal epithelium by diffusion.
Describe the Absorption of Lipids
1) Golgi modifies/processes triglycerides.
2) Combines triglycerides with proteins to form chylomicrons.
3) Packaged for release/exocytosis or forms vesicles.
4) Chylomicrons enter the lymphatic system, eventually draining into the circulatory system.
5) Triglycerides are hydrolysed by an enzyme in the endothelial layer of capillaries.
6) Fatty acids can then diffuse into cells.
Describe how oxygen goes from lungs to blood
1) Oxygen goes into alveoli and dissolves in the moist lining of alveolus.
2) Diffuses across alveolus epithelium and blood capillary epithelium
3) Picked up by red blood cells.
What are the adaptations of the lungs for exchange?
- Large SA:V ratio as many aveoli.
- Short diffusion pathway - single layer of epithelial cells and endothelial capillary walls.
- Partially permeable.
- Concentration gradient as constant ventilation/circulation replaces blood saturated with oxygen.
Describe the process of inspiration
1) External intercostal muscles contract.
2) Ribs move up and out.
3) Volume of thorax increases.
4) Diaphragm muscles contract - diaphragm flattens.
5) Volume increases (pressure decreases in thorax).
6) Air drawn in (atmospheric pressure bigger than pulmonary pressure).
Define Pulmonary Ventilation
Total volume of air moved into the lungs in one minute.
What is the equation for pulmonary ventilation?
Tidal Volume x Ventilation Rate