exammmm Flashcards
muscle fibers are made of ____
made of functional units of contraction called sarcomere
are contractile proteins
myofibril
bound by a network of interconnecting proteins called Z lines (contraction)
sarcomere
composed of a contractile protein (myosin molecules)
made up by each myosin molecule made of two heads and two tails
head has 2 binding sites_____
thick filaments
actin binding site and ATP binding site
Made of three proteins=actin, troponin, tropomyosin
thin filaments
binds myosin binding site on the Actin
Tropomyosin
has binding site for myosin protein that polymerizes to form in intertwined helix
actin
has three sub units
Actin binding site, tropomyosin binding site, calcium binding site
troponin
What are the binding sites on myosin?
actin binding site
Tropomyosin binding site
(thick filament)
what are the binding sites on actin
Troponin binding site, tropomyosin binding site
(thin filament)
voltage sensitive, calcium channels, known as (DHPR) located on _____
T tubules
action potentials at axon terminal stimulant release of
acetylcholine
Acetylcholine binds to _________ ______activating them, Na+ enters the cell
Acetylcholine receptors
DHPR activates receptors allowing Ca2+ release
ryanodine receptors
made of a neuron and all muscle fibers it innervates(very in size)
motor unit
slow oxidative
Mitochondria , resistance to fatigue, myoglobin
type 1
fast oxidative
Myosin ATPase activity, mitochondria, speed of contraction
type 2a
fast glycolytic
Myosin ATPase activity, glycolic enzyme, speed of contraction
type 2x
what are the ATP sources in skeletal muscles?
Glucose and fats (phosphocreatine energy Reservoir)
calcium vines to calmodulin forming CA2+
activates (MLCK) phosphorites myosin head and causes attachment
(detachment)
myosin light chain kinase