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1
Q

Explique la pathogénèse de l’anaphylaxie (1ère exposition et 2e exposition).

A

À la première exposition, le corps va produire des anticorps IgE, qui se fixeront aux mastocytes et aux granulocytes basophiles.
La deuxième exposition va provoquer la dégranulation des mastocytes et des leucocytes basophiles. Il y aura ensuite une libération massive de médiateurs chimiques (ex: histamine), de quoi va s’en suivre une réaction inflammatoire grave.

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