Exam3Lec7Adrenocortocosteroids

Question 1

What is the umberella term for GlLucocorticoids and mineralcorticoids?

Answer 1

Corticosteroids

Question 2

When was dexamethasone effective and not effective in hospitalized with Covid-19?

Answer 2

Effective: Ventilator (Severe Covid)
Not effective when no O2 was received (mild
Covid)
Very Careful with use

Question 3

Was administering intravenous corticosteroids effective for pts with significant head injury (severe brian injury)?

Answer 3

NO

Question 4

What is the issue with administereing Glucocorticpids in the US? What are some major side effects?

Answer 4

• Doctors over prescribe them
• incr risk of sepsis, blood clots, bone fractures, and can cause new onset diabetes (w/ short 1 time doses)

Question 5

What is secreted by the Adrenal gland in the
cortex ?
medulla?

Answer 5

• Cortex: adrenocorticosteroids & androgens (SEX HORMONES)
• Medulla: epinephrine (Catecholamines

Question 6

What does the outer zona glomerulosa secrete?

Answer 6

aldosterone which regulates Na+ (H2O) kidney reabsorption (MINERALCORTICOIDS)

Aldosterone is regulated by Renin-Angiotensin System

Question 7

What does the Middle zona fasciculata secrete?

Answer 7

cortisol which involved w/ metabolism & resistance to stress (GLUCOCORTICOIDS)

Question 8

What does the inner zona reticularis secrete?

Answer 8

dehydroepiandrosterone (DHEA (ANDROGENS)

Question 9

What is the highest level hormone?
Where is is released from?
What controls it secretion?

Answer 9

CRH (Corticotropin-releasing hormone)
CRH is released from the hypothalamus
CRH controls the secretion of ACTH

Question 10

Where is ACTH secreted from?