Exam3

Question 1

Compound consists of Ribose and Aresenate

Answer 1

Purine NucleoSIDE

Question 2

Compounds that generate nitrous acid (nitrates, nitrites, nitroamines) are what agents

Answer 2

Deaminating agents

Question 3

Dominate feature of the outer membrane of the cell wall GRAM NEGATIVE bacteria

Answer 3

Lipopolysaccharides (LPS)

Question 4

Helical DNA is most commonly found in the:

Answer 4

B FORM

Question 5

Which is a reducing sugar?

Answer 5

Look for hemiacetal (2&3 NOT 1)

Question 6

Which of the following is the Hairpin

Answer 6

AACAG

Question 7

What does FRUCTOSE obtain from Hydrolysis

Answer 7

Sucrose

Question 8

Biochemical property of lectins that is basis for their biological effects is ability to bind to:

Answer 8

Specific Oligosaccharides

Question 9

Helical RNA structure is

Answer 9

A Helix

Question 10

What do restrictive enzymes cut?

Answer 10

Palindrome sequences

Question 11

Concentration of GLYCATED Hemoglobin (GHB) in blood is an indicator of

Answer 11

Average glucose levels of 2 weeks before

Question 12

Helical RNA most common found in the ->

Answer 12

A FORM (RNA aaaarggg)

Question 13

How many chiral centers does D-tagatose have?

Answer 13

3 Chiral Centers

Question 14

Comparison with DNA-DNA double helices, stability of DNA-RNA and RNA-RNA helices is

Answer 14

RNA-RNA > DNA-RNA > DNA-DNA

Question 15

Lectins bind specifically to?

Answer 15

Carbohydrates

Question 16

Which of the following is a regulatory molecule

Answer 16

cAMP or cGMP

or ppGpp

Question 17

Which is a Heterosaccharide

Answer 17

Hyaluronate

Question 18

What modifies B DNA to Z DNA

Answer 18

Methylation of Cytosine

Question 19

5’ to 3’ on one strand of double stranded DNA is complementary to the __ to __ end of other

Answer 19

3’ to 5’

Question 20

Which of following is Palindrome?

Answer 20

• -GGATCC–

- -CCTAGG–

Question 21

Changes to DNA’s structure

Answer 21

Dimer formation
Depurination
Deamination

Question 22

Which of following statements is ture concerning this molecule pACGUAC

Answer 22

Nucleotide on the 5’ end has a phosphate group on its 5’ hydroxyl end

Question 23

Which of the following is not a reducing sugar?

Answer 23

Sucrose

Question 24

Three Important types of spontaneous reactions (chemical transformation of nucleotides and nucelic acids)

Answer 24

Deamination
Depurination
Dimer formation

Question 25

Which are Epimers?

Answer 25

G-gulose and D-Idose

Question 26

Lactose contains:

Answer 26

Gal (B1-4)Glu

Question 27

According to Watson Crick Model:

Answer 27

Perpendicular to Axis --OR-- Amount of A = Amount of T!!!

Question 28

Reduction of Osmotic Pressure in cells is due to

Answer 28

Polymerization of monosaccharides

Question 29

Which of following groups of double bond DNA require higher melting point

Answer 29

Whatever group has [Less A=T] or {MORE G=C}

Question 30

The polymer [5'] GTGATCAAGC [3'] can form double stranded structure with

Answer 30

[5']GCTTGATCAC[3']

Question 31

Base structure of a proteoglycan consists of a core protein and

Answer 31

Glycosaminoglycan

Question 32

Humans are unable to digest cellulose because

Answer 32

Beta- Anomers cannot be digested by human digestive enzymes but they can digest ALPHA Anomers

Question 33

Fehlings Regent, where there is no reaction it is due to

Answer 33

Sucrose

Question 34

Which of the following about Proteoglycans contain is false

Answer 34

Contain Peptide Cross-Links

Question 35

Oseltamivir and Zanamivir

Answer 35

Prevents viral proliferation by inhibiting neuraminidase

Question 36

Compare RNA vs DNA

Answer 36

RNA has 2' HYDROXYL GROUP

Question 37

Glycosaminoglycans do NOT contain

Answer 37

Proteins OR Carbohydrate Components

Question 38

E Coli with no vector (i) Transformin??? (ii) PBr332 (iii) PBr332 w/ tetracycline. Which would grow with ampicillin inserted

Answer 38

Type (i) [Transformin] | Type (ii) [PBr332]

Question 39

What is true about DNA

Answer 39

Phosphate group is negatively charged

Question 40

Which of the following statements concerning alternate forms of DNA is FALSE

Answer 40

Z form of DNA is wider and more compressed than B form

Question 41

Linear Form of Glucose forms a

Answer 41

Hemiacetal

Question 42

Linear Form of glucose cyclizes, the product is

Answer 42

Hemiacetal