Exam3 Flashcards

1
Q

Compound consists of Ribose and Aresenate

A

Purine NucleoSIDE

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2
Q

Compounds that generate nitrous acid (nitrates, nitrites, nitroamines) are what agents

A

Deaminating agents

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3
Q

Dominate feature of the outer membrane of the cell wall GRAM NEGATIVE bacteria

A

Lipopolysaccharides (LPS)

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4
Q

Helical DNA is most commonly found in the:

A

B FORM

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5
Q

Which is a reducing sugar?

A

Look for hemiacetal (2&3 NOT 1)

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6
Q

Which of the following is the Hairpin

A

AACAG

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7
Q

What does FRUCTOSE obtain from Hydrolysis

A

Sucrose

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8
Q

Biochemical property of lectins that is basis for their biological effects is ability to bind to:

A

Specific Oligosaccharides

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9
Q

Helical RNA structure is

A

A Helix

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10
Q

What do restrictive enzymes cut?

A

Palindrome sequences

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11
Q

Concentration of GLYCATED Hemoglobin (GHB) in blood is an indicator of

A

Average glucose levels of 2 weeks before

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12
Q

Helical RNA most common found in the ->

A

A FORM (RNA aaaarggg)

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13
Q

How many chiral centers does D-tagatose have?

A

3 Chiral Centers

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14
Q

Comparison with DNA-DNA double helices, stability of DNA-RNA and RNA-RNA helices is

A

RNA-RNA > DNA-RNA > DNA-DNA

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15
Q

Lectins bind specifically to?

A

Carbohydrates

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16
Q

Which of the following is a regulatory molecule

A

cAMP or cGMP

or ppGpp

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17
Q

Which is a Heterosaccharide

A

Hyaluronate

18
Q

What modifies B DNA to Z DNA

A

Methylation of Cytosine

19
Q

5’ to 3’ on one strand of double stranded DNA is complementary to the __ to __ end of other

A

3’ to 5’

20
Q

Which of following is Palindrome?

A
  • -GGATCC–

- -CCTAGG–

21
Q

Changes to DNA’s structure

A

Dimer formation
Depurination
Deamination

22
Q

Which of following statements is ture concerning this molecule pACGUAC

A

Nucleotide on the 5’ end has a phosphate group on its 5’ hydroxyl end

23
Q

Which of the following is not a reducing sugar?

A

Sucrose

24
Q

Three Important types of spontaneous reactions (chemical transformation of nucleotides and nucelic acids)

A

Deamination
Depurination
Dimer formation

25
Q

Which are Epimers?

A

G-gulose and D-Idose

26
Q

Lactose contains:

A

Gal (B1-4)Glu

27
Q

According to Watson Crick Model:

A

Perpendicular to Axis
–OR–
Amount of A = Amount of T!!!

28
Q

Reduction of Osmotic Pressure in cells is due to

A

Polymerization of monosaccharides

29
Q

Which of following groups of double bond DNA require higher melting point

A

Whatever group has [Less A=T] or {MORE G=C}

30
Q

The polymer [5’] GTGATCAAGC [3’] can form double stranded structure with

A

[5’]GCTTGATCAC[3’]

31
Q

Base structure of a proteoglycan consists of a core protein and

A

Glycosaminoglycan

32
Q

Humans are unable to digest cellulose because

A

Beta- Anomers cannot be digested by human digestive enzymes but they can digest ALPHA Anomers

33
Q

Fehlings Regent, where there is no reaction it is due to

A

Sucrose

34
Q

Which of the following about Proteoglycans contain is false

A

Contain Peptide Cross-Links

35
Q

Oseltamivir and Zanamivir

A

Prevents viral proliferation by inhibiting neuraminidase

36
Q

Compare RNA vs DNA

A

RNA has 2’ HYDROXYL GROUP

37
Q

Glycosaminoglycans do NOT contain

A

Proteins OR Carbohydrate Components

38
Q

E Coli with no vector (i) Transformin??? (ii) PBr332 (iii) PBr332 w/ tetracycline. Which would grow with ampicillin inserted

A

Type (i) [Transformin]

Type (ii) [PBr332]

39
Q

What is true about DNA

A

Phosphate group is negatively charged

40
Q

Which of the following statements concerning alternate forms of DNA is FALSE

A

Z form of DNA is wider and more compressed than B form

41
Q

Linear Form of Glucose forms a

A

Hemiacetal

42
Q

Linear Form of glucose cyclizes, the product is

A

Hemiacetal