Exam3 Flashcards
Compound consists of Ribose and Aresenate
Purine NucleoSIDE
Compounds that generate nitrous acid (nitrates, nitrites, nitroamines) are what agents
Deaminating agents
Dominate feature of the outer membrane of the cell wall GRAM NEGATIVE bacteria
Lipopolysaccharides (LPS)
Helical DNA is most commonly found in the:
B FORM
Which is a reducing sugar?
Look for hemiacetal (2&3 NOT 1)
Which of the following is the Hairpin
AACAG
What does FRUCTOSE obtain from Hydrolysis
Sucrose
Biochemical property of lectins that is basis for their biological effects is ability to bind to:
Specific Oligosaccharides
Helical RNA structure is
A Helix
What do restrictive enzymes cut?
Palindrome sequences
Concentration of GLYCATED Hemoglobin (GHB) in blood is an indicator of
Average glucose levels of 2 weeks before
Helical RNA most common found in the ->
A FORM (RNA aaaarggg)
How many chiral centers does D-tagatose have?
3 Chiral Centers
Comparison with DNA-DNA double helices, stability of DNA-RNA and RNA-RNA helices is
RNA-RNA > DNA-RNA > DNA-DNA
Lectins bind specifically to?
Carbohydrates
Which of the following is a regulatory molecule
cAMP or cGMP
or ppGpp
Which is a Heterosaccharide
Hyaluronate
What modifies B DNA to Z DNA
Methylation of Cytosine
5’ to 3’ on one strand of double stranded DNA is complementary to the __ to __ end of other
3’ to 5’
Which of following is Palindrome?
- -GGATCC–
- -CCTAGG–
Changes to DNA’s structure
Dimer formation
Depurination
Deamination
Which of following statements is ture concerning this molecule pACGUAC
Nucleotide on the 5’ end has a phosphate group on its 5’ hydroxyl end
Which of the following is not a reducing sugar?
Sucrose
Three Important types of spontaneous reactions (chemical transformation of nucleotides and nucelic acids)
Deamination
Depurination
Dimer formation
Which are Epimers?
G-gulose and D-Idose
Lactose contains:
Gal (B1-4)Glu
According to Watson Crick Model:
Perpendicular to Axis
–OR–
Amount of A = Amount of T!!!
Reduction of Osmotic Pressure in cells is due to
Polymerization of monosaccharides
Which of following groups of double bond DNA require higher melting point
Whatever group has [Less A=T] or {MORE G=C}
The polymer [5’] GTGATCAAGC [3’] can form double stranded structure with
[5’]GCTTGATCAC[3’]
Base structure of a proteoglycan consists of a core protein and
Glycosaminoglycan
Humans are unable to digest cellulose because
Beta- Anomers cannot be digested by human digestive enzymes but they can digest ALPHA Anomers
Fehlings Regent, where there is no reaction it is due to
Sucrose
Which of the following about Proteoglycans contain is false
Contain Peptide Cross-Links
Oseltamivir and Zanamivir
Prevents viral proliferation by inhibiting neuraminidase
Compare RNA vs DNA
RNA has 2’ HYDROXYL GROUP
Glycosaminoglycans do NOT contain
Proteins OR Carbohydrate Components
E Coli with no vector (i) Transformin??? (ii) PBr332 (iii) PBr332 w/ tetracycline. Which would grow with ampicillin inserted
Type (i) [Transformin]
Type (ii) [PBr332]
What is true about DNA
Phosphate group is negatively charged
Which of the following statements concerning alternate forms of DNA is FALSE
Z form of DNA is wider and more compressed than B form
Linear Form of Glucose forms a
Hemiacetal
Linear Form of glucose cyclizes, the product is
Hemiacetal
