Exam(s) MCQ Deck Flashcards
In coordination chemistry the donor atom of a ligand is___________
the atom in the ligand that shares an electron pair with the metal
The biological functions of carbonic anhydrase and alcohol dehydrogenase, respectively are__________.
Hydration of CO2 to bicarbonates, alcohols, and aldehydes
The active sites of carboxypeptidase A contain _______ and catalyze ________ .
Zn(II); the hydrolysis peptide bonds
Which of the following represents the correct set of essential elements?
Fe, Na, K, Zn
The amino acid side chain with high affinity for Ca2+ and Cu2+ in metallo-proteins is __________.
Carboxylate from glutamate for Ca2+ and imidazole from histidine for Cu2+
Which biologically active species control important cellular processes such as hydrolysis?
Metallo-proteins
How is acid-base catalysis accomplished in biological processes?
Through metal ion built-in protein structures
The magnesium-containing 1,5-biphosphate enzyme (ribusco enzyme) is of great interest because_________.
It removes CO2 gas in the atmosphere and fixing it into other products
What are Arginases?
Arginases are Mn(II) containing metalloenzymes that catalyze the hydrolysis of nitrogen-containing proteins to produce urea as the byproduct.
Zinc finger motifs are particular characteristics of proteins that function as
Gene regulators
Metallothioneins are _________
cysteine-containing ligands that bind mainly soft metal ions
In biological systems, the metal ion involved in O2 transport besides Fe is___________.
Cu (copper)
Which biomolecules are prone to the irreversible oxidative damage caused by reactive oxygen species (ROS)_________.
DNA, Lipids, Proteins, Carbohydrates
The number of O2 molecules that hemoglobin can transport is ___________.
Four
The amino acid side chains that act as ligands for the binding of Fe3+ in transferrin are ___________.
Tyrosine, histidine, and aspartate
Which one of the following is not the direct reduction products of O2, which are commonly known as reactive oxygen species (ROS)___________?
O3
The ligand system found in hemoglobin and myoglobin is__________.
Porphyrin
The biological function of Myoglobin is___________.
None of the above
Myoglobin stores oxygen!
The proteins which act as oxygen transport in small organisms are __________.
Hemocyanin and hemerythrin
Which one of the following is NOT the essential function of calcium in biological systems?
Transport of dioxygen
Important Functions: Nerve signaling, enzyme catalysis, structural support in proteins, muscle movement
The toxic exposure of children to mercury and cadmium contamination is treated by chelation therapy mainly using amino acid ligands that contain ________ residue
Cysteine
Iron-Sulfur clusters in biological systems are involved in__________.
Electron transfer
Superoxide dismutase contains the metal ions________.
Cu(II) and Zn(II)
A well-known naturally occuring organometallic compound is________
Vitamin B12 coenzyme
The main biological function of cytochrome-c oxidase is __________.
Reduction of O2 to water
Cytochrome-C is __________.
Heme protein
What is the molecular basis of the mode of action for Pt(II) chemotherapy agents?
Formation of a stable complex between DNA and Pt(II) resulting in the bending of DNA helix and partial unwinding
The active site of oxygen atom transfer enzymes contain________.
Mo (molybdenum)
Which one of the following complex/s shows activity against cancerous cells?
All complexes are active agents
