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Pharm > Exam Neur > Flashcards

Exam Neur Flashcards

1
Q

Donepezil choliniterase inhibitor complications

A

GI
upset
muscle
cramps
hallucinations
dysrhythmias
dysuria

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2
Q

Mementine definition

A

Stops nerve damage in the brain

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3
Q

Mementine complications

A

Respiratory distress
depression
hallucinations
headache
constipation

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4
Q

Converts to dopamine in the brain but gets metabolized at a high rate in the blood-brain barrier

A

Levodopa / Carbidopa

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5
Q

Prevents the rapid breakdown of levodopa, which allows less levodopa to be given, thus decreasing potential complications

A

Carbidopa

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6
Q

Complications of levodopa / Carbidopa

A

•GI
•diskenzia - involuntary muscle movements
•dystonia - muscle spasms
•Tachycardia
•hallucinations
•delirium

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7
Q

Pramipexole, Ropinirole, Bromocriptine definition and complications

A

It is a dopamine Agonist
Dyskenzia
hallucinations
delirium
orthostatic hypotension

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8
Q

Amantadine

A

•Dopamine releaser
•Anticholinergic effects

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9
Q

What is phenytoin used for

A

It’s a anticoagulant med

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10
Q

Phenytoin =

A

Phenytoxic
10-20 therapeutic range

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11
Q

Phenytoin and Fosphenytoin complications

A

Gingival hyperplasia

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12
Q

You should avoid giving phenotine with food that has protein true or false

A

True
Give medication 1 hour before or two to three after and decrease the dose with liver failure hypoalbumemia

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13
Q

Phenytoin toxicity adverse effects

A

Rash
suicidal ideation
unstable gate or ataxia
tremors

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14
Q

It is an anticholinergic and is used to treat dyskinesia and dystonia from Parkinson’s medications and EPS symptoms complications anticolonergic effects CNS depression

A

Benztropine

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15
Q

Seizure medication and the CNS depression

A

Hypotension
Bradycardia
Respiratory depression
Increase risk for Falls
Sedation increases seizure threshold can lead to a lowering of the threshold for some types of seizures

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16
Q

Seizure medication can increase

A

Vitamin D and calcium

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17
Q

Bone marrow suppression / blood dyscrasias and seizure meds

A

Anemia
Weakness
Lethargic
Decreases white blood cells
Increases risk for infections
Decreases platelets
Increases risk for bleeding
Steven Johnson syndrome
Avoid pregnancy
Liver failure

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18
Q

Barbiturates

A

○Phenobarbital
○Theopenital

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19
Q

Benzodiazepines ends in

A

-Pams
-Lam’s

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20
Q

What risk does benzodiazepine cause

A

Respiratory depression antidote ○Flumazenil/ Romazicon

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21
Q

What drug is the drug of choice for status epilepticus given for someone actively having a seizure through IV

A

Benzodiazepine

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22
Q

What is the range for phenobarbital and theopenital

A

10-40

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23
Q

What is the range for Phenytoin and Fosphenentoin

A

10 to 20

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24
Q

Range for carbamazepine

A

4-12

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25
Carbamazepine definition
Decreased seizure threshold for absence seizures Less sedating
26
What is the significant risk for carbamazepine
Bone marrow depression and hyponatremia
27
Ethosuximide range
50-100
28
What is the only use for Ethosuximide
Absent seizures
29
Valproate/Valproic acid range
50-100
30
Protein binding medication avoid giving with food that has protein, get medication 1 hour before or 2 to 3 after and decrease the dose with liver failure (hypoalbumemia) Don't make Sprinkles with carbonated beverages
Valproate / Valproic acid
31
Pregabalin side effects
CNS depression Edema Weight gain
32
What are the complications that lamotrigine cause
CNS depression Steven Johnson syndrome Vision changes
33
Pregabalin causes
CNS suppression Weight gain Edema
34
Complications of this medication cause hyponatremia and bone marrow suppression
Oxcarbazepine
35
This medications complications cause CNS depression Elevated ammonia levels (assess liver function in mental status) Decrease electrolytes
Topiramate
36
Meds for Alzheimers
Donepezil Memantine
37
Parkinson disease medications
Levadopa/carbadopa Pramipexole Ropinirole Bromocriptine Amantadine Benzotropine
38
Meds for Seizures
Phenobarbital Thiopenital Phenytoin Fosphenytoin Lam or Pam Carbamazepine Ethosuxsimide Valproate / valproic acid Lamotrigine Levetiracetam Gabapentin Pregabalin Oxcarbazepine Topiramate Lacosemide
39
This drug is used to treat dyskinesia and dystonia from Parkinson's medications and EPS symptoms complications anticholinergic effects CNS depressant
Benztropine
40
Complications of this medication include hyponatremia and bone marrow suppression
Oxcarbazepine
41
Days drugs complications are CNS depression, elevated ammonia levels (assess the liver function and mental status) decreased electrolytes
Topiramate
42
Lacosamide complications include
Euphoria cardiac complications orthostatic hypotension irregular rhythms
43
Mucinaric Agonist medication
Bethanechol
44
Bethanichol MOA
For non obstructive urinary retention, promotes urination
45
Complications of bethanichol
Polyuria bradycardia hypotension
46
Is Bethanichol cholinergic or anticholinergic?
Cholinergic
47
Mucarinic antagonist Med
Oxybutynin
48
Oxybutynin MOA
Overactive bladder / bladder spasms
49
What are the complications of oxybutynin
Anticholinergic effects urinary retention
50
Non-depolarizing agents meds
-cur-
51
Is the non-dipolarizing agents reversible?
Yes
52
Are the depolarizing agents reversible?
No
53
Succinylcholine/Sux complications
Malignant hyperthermia - treatment is dantrolene Hyperkalemia - check potassium and kidney function before giving
54
Muscle relaxant drugs
Diazepam Cyclobenzaprine Baclofen Metaxalone
55
Complications of muscle relaxants
CNS depression Drowsiness Dizziness Hepatic failure (dantrolene)
56
Dystonia, Akathisia (inner restlessness), Tardiness dyskinesia (ticks), are all signs of what
EPS
57
Fever, encephalopathy, unstable vitals, elevated enzymes, rigid muscles I
Nms
58
Complications of haloperidol
CNS depression EPS NMS Anticholinergic Seizures Agranulocytosis Liver and kidney failure Prolong QT intervals
59
Chlorpromazine complications
CNS depression EPS NMS Anticolinergic Agranulocytosis Prolong QT intervals
60
A typical antipsychotic drugs
Clozapine Olanzapine Quetiapine Aripiprazole
61
Atypical antipsychotic complications
EPS Agranulocytosis Anticolinergic Seizures Prolonged QT intervals Labile glucose Hyperlipidemia
62
Selective serotonin reuptake inhibitor medications
Serotoline Fluoxetine escitalopram
63
Complications with sertraline fluoxetine and escitalopram
Decrease compliance due to sexual dysfunction Weight gain Suicide Hyponatremia Osteoporosis Dysrhythmias
64
Serotonin syndrome
GI abdominal cramping bloating diarrhea anxiety shivering Tremor hyperflexia tachycardia hypertension manic like symptoms confusion hallucinations spreading fever agitation
65
Tricyclic antidepressants
Amitriptyline
66
Amitriptyline complications
Anticholinergic Orthostatic hypotension Weight gain Dysrhythmia Seizures Suicide
67
Phenelzine Isocarboxazide Complications
Anticholinergic effects Liver failure Hyponatremia Hypertensive crisis Stiff neck Nausea vomiting Sweating Sharply elevated blood pressure Occipital headache
68
What to avoid on Phenelzine isocarboxazide
Avoid foods with Tyramine Caffeine Age processed foods Deli meats Beer cheese and wine
69
Bupropion complications
Anticholinergic Suicidal Hypertension Seizures Anorexia
70
Mirtazapine complications
Sedation Orthostatic hypotension Wash out period for MAOI's and SSRI's
71
Complications for Trazodone
Sedation Orthostatic hypotension Sexual dysfunction
72
DDI for Trazodone
Delanton and digoxin increase level

Pharm (3 decks)

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