Exam IV: HIV Drugs (Protease Inh.) Flashcards

1
Q

Atazanavir

A
3-Letter: ATV
Class: Protease Inhibitor
Brands: Reyataz, Evotaz
Dose/Frequency: 
300mg + 100mg RTV 
OR
400mg (if RTV not tolerated)
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2
Q

Atazanavir

A
3-Letter: ATV
Class: Protease Inhibitor
Dose/Frequency: 
300mg + 100mg RTV 
OR
400mg (if RTV not tolerated)
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3
Q

a

A

3-Letter:
Class:
Dose/Frequency

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4
Q

a

A

Common:
Serious:

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5
Q

ATV

A

Azatanavir
Common: N/V, rash, increased serum cholesterol, fever, cough, serum bilirubin, jaundice
Serious: Breathing conduction problems, hepatic/renal impairment

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6
Q

Darunavir

A

3-Letter:
Class: Protease Inhibitor
Dose/Frequency:

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7
Q

a

A

Common:
Serious:

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8
Q

a

A

3-Letter:
Class: Protease Inhibitor
Dose/Frequency:

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9
Q

a

A

Common:
Serious:

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10
Q

a

A

3-Letter:
Class: Protease Inhibitor
Dose/Frequency:

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11
Q

a

A

Common:
Serious:

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12
Q

ATV

A

Azatanavir
Common: N/V, rash, increased serum cholesterol, fever, cough, serum bilirubin, jaundice
Serious: Breathing conduction problems, hepatic/renal impairment

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13
Q

Darunavir

A
3-Letter: DRV
Class: Protease Inhibitor
Brands: Prezista, Prezcobix
Dose/Frequency: 
800mg + RTV 100mg QD (NAIVE OR RAMS)
600mg + RTV 100mg BID (EXPERIENCED)

**Prezcobix: 1 TAB QD

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14
Q

DRV

A

Darunavir
Common: N/V, diarrhea
Serious: Severe rash, hepatoxicity

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15
Q

Fosamprenavir

A
3-Letter: FPV
Class: Protease Inhibitor
Brands: Lexiva
Dose/Frequency: 
1400mg + 100-200mg RTV QD (NAIVE)
700mg + 100mg RTV BID (EXPERIENCED)
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16
Q

FPV

A

Fosamprenavir
Common: N/V, diarrhea, headache
Serious: Hemolytic anemia

17
Q

Indinavir

A
3-Letter: IDV
Class: Protease Inhibitor
Brands: Crixivan
Dose/Frequency: 
800mg q8h (UNBOOSTED)
800mg + 100mg RTV (BOOSTED
18
Q

IDV

A

Indinavir
Common: GI issues, headache, rash, dizziness, alpecia
Serious: Thrombocytopenia, hemolytic anemia

19
Q

Lopinavir

A
3-Letter: LPV/r
Class: Protease Inhibitor
Brands: Kaletra
Dose/Frequency: 
2 TAB BID
4 TAB QD
20
Q

LPV/r

A

Lopinavir
Common: N/V, diarrhea, abdominal pain
Serious: QTc prolongation, altered cardiac conduction

21
Q

Lopinavir

A
3-Letter: LPV/r
Class: Protease Inhibitor
Brands: Kaletra
Dose/Frequency: 
2 TAB BID
4 TAB QD
22
Q

LPV/r

A

Lopinavir
Common: N/V, diarrhea, abdominal pain
Serious: QTc prolongation, altered cardiac conduction

23
Q

Nelfinavir

A
3-Letter: NFV
Class: Protease Inhibitor
Brands: Viracept
Dose/Frequency: 
1250mg BID
750mg TID
24
Q

NFV

A

Nelfinavir
Common: N/V, abdominal pain, rash, elevated LFTs
Serious: Hepatic impariment

25
Q

Ritonavir

A
3-Letter: RTV
Class: Protease Inhibitor
Brands: Norvir
Dose/Frequency: 
300mg BID then 600mg BID
26
Q

RTV

A

Ritonavir
Common: N/V, diarrhea, dyspepsia, abdominal pain, fatigue, dizziness, rash, cough
Serious: Edema, peripheral neuropathy

27
Q

Saquinavir

A
3-Letter: SQV
Class: Protease Inhibitor
Brands: Invirase
Dose/Frequency:
1000mg + 100mg RTV BID
28
Q

SQV

A

Saquinavir
Common: N/V, rash, fatigue
Serious: QTc prolongation risk

29
Q

Tipranavir

A
3-Letter: TPV
Class: Protease Inhibitor
Brands: Aptivus
Dose/Frequency:
500mg + 200mg RTV BID
30
Q

TPV

A

Tipranavir
Common: N/V, diarrhea, rash,
Serious: hepatotoxicity, intracranial hemorrhage