exam III review flashcards

1
Q

hemicholiniums

A

block uptake of choline via CHT into neuron terminal

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2
Q

uses VAT to enter vesicle v. uses VMAT to enter vesicle

A

VAT cholinergic

VMAT adrenergic

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3
Q

vesamicol

A

inhibits cholinergic entry to vesicle with VAT

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4
Q

botulinum toxin

A

prevents choinergic release

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5
Q

AchE inhibitors/neostigmine

A

block hydrolysis of Ach via AchE

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6
Q

rate limiting step of adrenergic synthesis

A

tyrosine –> dopa

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7
Q

metyrosine

A

inhibits conversion tyrosine to dopa

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8
Q

reserpine

A

inhibits adrenergic transport into vesicles via VMAT

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9
Q

bretylium

A

inhibits adrenergic release by inhibiting VAMP

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10
Q

cocaine and tricyclic antidepressants

A

block neuronal reuptake of adrenergics

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11
Q

corticosteroids

A

block extraneuronal reputake via NET2 of adrenergics

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