Exam II Flashcards

1
Q

What is the life span of a RBC?

A

120 days

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2
Q

Which 3 values tell you there may be an anemia?

A
  • RBC
  • Hgb
  • Hct
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3
Q

Which 3 values tell you what kind of anemia it is?

A
  • MVC
  • MCH
  • MCHC
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4
Q

What RBC information does MCV give?

A

size (volume)

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5
Q

What RBC information does MCH give?

A

weight (amount of Hgb)

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6
Q

What RBC information does MCHC give?

A

concentration

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7
Q

What levels are inc./dec. in microcytic hypochromic anemia?

A
  • decreased MCV

- decreased MCH/MCHC

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8
Q

What levels are inc./dec. in normocytic normochromic anemia?

A
  • normal MCV

- normal MCH/MCHC

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9
Q

What levels are inc./dec. in macrocytic normochromic anemia?

A
  • increased MCV

- normal MCH/MCHC

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10
Q

What levels are inc./dec. in macrocytic hyperochromic anemia?

A
  • increased MCV

- increased MCH/MCHC

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11
Q

What is anemia caused by?

A
  • decreased production
  • increased breakdown
  • blood loss
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12
Q

What are etiologies of microcytic hypochromic anemia?

A
  • iron deficiency anemia*
  • anemia of chronic dx
  • thalassemia
  • chronic blood loss
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13
Q

What are etiologies of macrocytic normochromic anemia?

A
  • vit B12 deficiency*
  • folic acid deficiency*
  • alcoholism
  • liver dx
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14
Q

What are etiologies of normocytic normochromic anemia?

A
  • anemia of chronic dx*
  • acute blood loss
  • hemolytic anemia (sickle cell)
  • aplastic anemia
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15
Q

What is the MC worldwide cause of anemia?

A

iron deficiency anemia

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16
Q

What is the MC etiology of iron deficiency anemia (in general)?

A

GI tract bleeding

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17
Q

What is the MC etiology of iron deficiency anemia in developed countries?

A

blood lost during menses

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18
Q

Leukopenia is typically seen with what type of infection?

A

viral

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19
Q

Leukocytosis is typically seen with what type of infection?

A

bacterial

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20
Q

What are neutrophils essential for?

A
  • phagocytic action

- pyogenic infxns

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21
Q

What are eosinophils essential for?

A
  • allergy
  • drug rxn
  • parasites
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22
Q

What are basophils essential for?

A
  • hypersensitivity rxn

- parasites

23
Q

What are lymphocytes essential for?

A

fight viral infxn

24
Q

What are monocytes essential for?

A

help neutrophils

25
0-5,000 WBC
Leukopenia
26
5-10,000 WBC
normal
27
>10,000 WBC
leukocytosis
28
High WBC count is indicative of what?
bacterial infxn
29
Low WBC count is indicative of what?
viral infxn
30
10-18,000 WBC
typical infxn/inflam
31
18-20,000 WBC
"hot abdomen"
32
20/30-50,000
leukamoid rxn | leukemia
33
>50,000
leukemia
34
What does a right shift indicate?
more mature cells
35
What does a left shift indicate?
more immature cells
36
What is the stem cell theory?
if one cell type increases, others decrease
37
Neutrophilia is usually due to?
bacterial infxns
38
Neutropenia is usually due to?
viral infxn
39
Hypersegmented neutrophils are seen with what condition?
megaloblastic anemia
40
What is the MC cause of lymphocytosis?
viral infxns
41
What is the MC cause of lymphopenia?
bacterial infxns
42
What do B-lymphocytes do?
tag foreign bodies and produce antibodies
43
What do T-lymphocytes do?
kill foreign bodies
44
What do B-lymphocytes ultimately turn into?
plasma cell
45
What is the "inverted ratio"?
lymphocytes > neutrophils | -seen in viral infxns
46
Neutrophilic leukocytosis with 16 WBC. What is the ML dx?
bacterial infxn
47
Lymphocytic leukocytosis with 16 WBC. ML dx?
viral infxn
48
Lymphocytosis with 3.8 WBC. ML dx?
viral infxn
49
What type of cells does HIV kill?
CD4+ T cells
50
When is an individual diagnosed with AIDS?
when the CD4 count drops below 200
51
What does the CD4 count tell us?
how well the immune system is fxning
52
What does the viral load test tell us?
how rapidly HiV is progressing
53
The presence of what cells indicate acute leukemia?
blasts and pros
54
What is the MC leukemia found in the first few months?
AML