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Exam II Flashcards

1
Q

⬇️phylloerythrin excretion in BILE in 🌱herbi
⬆️phyllo in serum
⚡️❇️phyllo➡️skin lesions

A

Photosensitize

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2
Q

End stg liver/portosys shunt ➡️

Abnorm NT

A

Hepatic encephalopathy

Liver atrophy

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3
Q

⬇️syn

Chronic portal hypertension: ⬆️ 2• loss

A

Hypoalbumenemia

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4
Q

Hyperbilirubinemia

A

Icterus➡️ hepatic dis, cholestasis, intra/extra-vasc hemolysis

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5
Q

Intrahepatic cholestasis

A

Toxin/bact/virus/ischemia

⬇️bile secr

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6
Q

Extrahepatic cholestasis

A

Neoplasia/parasite/inflam➡️bile obstruction

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7
Q

Liver injury response

A

FRB

Fibrosis: 🔼stellate➡️myofiboblast:❇️col syn
Regen: req reticul net & oval cells⏩nodules
Bile duct hyperplasia: 1• cholestasis

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8
Q

Centrilobar fibrosis

A

Chronic R♥️ fail /toxin

🐶mycotoxin (Asper.flavus)
[Cu] 🐑

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9
Q

Perilportal fibrosis

A

Chronic in🔥/bil obs/toxin

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10
Q

Causes of accentuated lobar pattern liver

picture

A

Necrosis
Herpes ➡️ multifocal necrosis
Lipidosis

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11
Q

Unusual:
🐷 &🐎aflatoxicosis
🐱hexachlorophene
[Cu] 🐑

Liver pattern

A

Midzonal necrosis

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12
Q

Hepatic lipidosis

picture

A

Diet/tissue FA ➡️ liver 🔼TG apoprotein
Acum TG>metab degrad/rel➡️hepatomegaly/greasy friable & floats

GCC➡️❇️ glycogen synthase: ⬆️glycogen storage

Ketosis🐄
DM
Hyperlipidemia 🐎

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13
Q

Focal necrosis & 2• hepatitis

A

Clost. piliformes

🐎foals/🐄 rumenitis➡️damage mucosa➡️portal v.➡️liver infx

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14
Q

Chronic lymphocytis cholangitis

A

1• 🐱 >4yr

Icterus/intrahep cholestasis
In🔥 portal areas around bile ducts➡️ BILE DUCT Prolif & fibrosis

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15
Q

Neoplasm liver

Neoplasm Mm

A

Metastasis > primary neo

Rhabdomyosarcoma: local aggressive w/ early infil… Metastasis rare

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16
Q

Pancreatitis

A

🐶🐱 rel ELASTASE + Phospholipase A➡️ tissues➡️🔥 + digestion➡️acute hemorr + necrosis ⏩ DIC

Chronic: fibrosis + atrophy

17
Q

Mm hypertrophy

A

IGF-1:❇️kinases mtor➡️❇️protein syn
⛔️Mm breakdown

Myostatin: reg stem cell growth=⬆️# fibers/cytoplasm + l

18
Q

⛔️GABA + Glycine rel NMJ

A

Teranus ➡️ rigid paralysis

19
Q

⛔️fusion + Ach rel

A

Botulism ➡️ flaccid paralysis

20
Q

Acq: 🐶 common; auto-Ab bind AchR
Inherit: uncommon; ⬇️#AchR or fn

A

Myasthenia gravis

21
Q

Segmental necrosis

A

Nutrition/toxic

Acute vacuoles: swollen round pink
Coag fibers: ⬇️Mm fibers/hyaline degen **pic
Irrev necrosis: ⬇️striations

22
Q

Uniform necrosis

A

Monophasic: 1 dose toxin/exertion/ionophores

Short duration: multifocal pallor lesion
🚫mineralization

23
Q

Multiple necrosis

A

Repeated injury

Nutrional vitE+[Se] def ➡️ ROS

24
Q

Nutrional myopathy

A

1• type I postural fibers
WMD

Pale Mm (⬇️myoglobin) +/- minerals

25
Q

Exertional Rhabdomyolysis

A

Acute sev necrosis, exercise to death➡️ latic acidosis

Leaky PM // ⬇️Myoglobin
⬆️ catechol rel➡️ SNS exhaust⏩ ⬇️nutrients to Mm

26
Q

Neurogenic atrophy

A

BOTH type I + II

Rapid + renervation⏩ 1 Mm type

27
Q

Cachexia/disuse/endocrine

A

Type II

Slow

28
Q

Strep suis 💉 Myositis

A

Suppurative granulomatous

29
Q

🔪wound infx➡️ skin/fascia/Mm

Introduce Clost spores➡️pale Mm + gas bubbles

A

Malignant edema

30
Q

1• young; Clost spores alrdy in Mm.

Trauma/injury:❇️anaerobic env➡️ Clost chovei prolif + toxins ➡️ hemorr + necrosis

A

Black leg

31
Q

1• mascutory Mm 🔥
Acute swell➡️atrophy
Chronic ➡️fibrosis

A 
Imm-med myositis
Mascitory myositis (T+B cells)

🚫open jaw
May spread polymyositis (T-cells)
Viszla + corgi

32
Q

Muscular dystrophy

A

Concurrent degen + regen➡️ scattered atrophy pattern

33
Q

Steatosis /lipomatosis

A

Fat infiltrate shoulder cut Mm 🐄🐷
dDx neoplasm
🚫⬆️size

34
Q

Tendon injury

A

Granulation tissue ⬆️matrix⬇️elasticity fn

1• SDFT + Suspensory lig

Sp path (4 decks)

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