Exam Concept Review: Chapter 26 Flashcards
What can severe or prolonged stress cause?
Increase wear and tear on tissues
Exhaustion of resources
Exacerbation of chronic conditions
What are the significant effects of stress?
Think sympathetic nervous system (fight or flight response):
Elevated blood pressure
Bronchodilaton and increased ventilation
Increase blood glucose levels:
Need sugar for energy
Arousal of central nervous system
Decrease inflammatory and immune response:
Not important pieces when running away or fighting a enemy
What is General Adaptation Syndrome (GAS)?
Alarm stage (everything gets activated): Mobilization of defenses (hypothalamus, sympathetic nervous system, adrenal glands)
Resistance stage (everything is elevated - body is going operate at a peak performance level): Elevation of hormonal levels (body systems operate at peak performance levels)
Final stage (exhausted all resources - “Exhaustion Stage”): Resolution or death stage
What are the potential effects of prolonged or severe stress?
Renal failure (decrease blood flow because we won’t need to pee to fight or runaway from an enemy): Prolonged severe vasoconstriction
Ischemia causes cell damage
Stress ulcers:
Vasoconstriction and glucocorticoids (“steroids”)
Decrease in mucosal generation and mucus production
Infection:
Depression of the inflammatory and immune responses
Slowed healing (due to all the processes):
Following trauma or surgery
Increase secretion of Glucocorticoid- reduction in protein synthesis and tissue regeneration
Increased catecholamine levels- vasoconstriction, reduced nutrients and oxygen to tissue
Post-traumatic stress disorder:
Serious consequence of major disaster or personal threat
Usually occurs within 3 months of event (may cause symptoms years later)
High risk of developing dependence on drugs and/or alcohol
What does endorphin do?
Blocks pain
Ex: this is how someone who is in a car accident can just walk away because the endorphins kicked in)
What are the specific problems related to stress and disease?
Headache: may develop during or after stress response
Stomatitis (ulcers in mouth) and necrotizing periodontal disease
Prolonged vasoconstriction:
Can impair function or necrosis in Gastrointestinal tract or kidneys
Vessels are constricting to keep heart rate and blood pressure up (sympathetic vs parasympathetic)
Precipitating factor:
Chronic infections
Physical and/or emotional distress