EXAM

Question 1

Receptor Agonist?

Answer 1

binds with the receptors and causes a corresponding effect in the cell. same effect as the bodys own neurotransmitter

Question 2

Receptor Antagonist?

Answer 2

binds with the receptor but prevents there being any effect in the cell. is a blocker drug

Question 3

Receptor Up regulation?

Answer 3

chronic absence of agonist (over-stimulation of hormone)

Question 4

Receptor Down regulation?

Answer 4

chronic excess of agonist (not enough hormone)

Question 5

Pharmacodynamics?

Answer 5

how the drug works by binding with the target receptors

Question 6

Pharmacokinetics?

Answer 6

getting the drug into the body, through the circulation and removed from the body (ADME)

Question 7

Hepatic First-Pass Metabolism?

Answer 7

liver can metabolise some of the drug prior to it reaching systemic circulation

Question 8

Buccal and Sublingual?

Answer 8

sublingual is under the tongue and buccal is cheek

Question 9

Parenteral administration, Subcutaneous (SC)?

Answer 9

beneath the skin into hypodermis, slow absorption rate.

Question 10

Parenteral administration, Intramuscular (IM)?

Answer 10

faster absorption than SC

Question 11

Parenteral administration, Intravenous (IVI)?

Answer 11

immediately into the blood, bolus dose

Question 12

Parenteral administration, Epidural?

Answer 12

into spinal canal, outside dura matter

Question 13

Topical Administration?

Answer 13

skin through local effect by ointment and same for eyes, ears and nose

Question 14

The Protein Drug Album? (through distribution)

Answer 14

some drugs are carried in blood bound to albumin and are less free to be distributed

Question 15

Enterohepatic Circulation?

Answer 15

drugs can be cycled through liver and small intestine

Question 16

Prodrugs?

Answer 16

drugs which are metabolised into their more active form

Question 17

Therapuetic Range?

Answer 17

drug concentration in the blood which produces clinical benefits