exam 7

Question 1

glyburide

Answer 1

sulfonylurea that inhibits Katp channel

Question 2

rapaglinide

Answer 2

meglitinide that inhibits katp channel

Question 3

“glitazone”

Answer 3

PPARy agonist –> inc insulin sensitivity

Question 4

acarbose

Answer 4

a-glucosidase inhibitor –> inhib breakdown of carbs + oligosaccharides

Question 5

pramlitide

Answer 5

amylin –> sup glucagon, dec gastric emptying

Question 6

exendatide

Answer 6

GLP-1 agonist –> inc insulin syn, dec gastric emptying

Question 7

sitagliptin

Answer 7

DPP-4 inhibitor –> inc incretin –> inc insulin + dec glucagon

Question 8

canagliflozin

Answer 8

SGLT2 inhibitor –> dec glucose reab

Question 9

hydralazine

Answer 9

dec afterload, post MI

Question 10

nitroprusside

Answer 10

dec preload + afterload, ICU via IV

Question 11

nesiritide

Answer 11

vasodilate (inc cGMP) + diuretic, ICU via IV

Question 12

isosorbide dinitrate + nitroglycerin

Answer 12

dec preload, long term=tolerance

Question 13

vaptans (ADH antag)

Answer 13

IV tx of hospitalized pt with hyponatremia + CHF + syndrome of inappropriate ADH secretion, DONT REDUCE MORTALITY