Exam 6 module 10 pharma

Question 1

Dyslipidemia medications

Answer 1

Atorvastatin
cholestyramine
ezetimibe
gemfibrozil
niacin (VB3/nicotinic acid)

Question 2

Atrovastatin MOA, AE

Answer 2

lowers cholesterol and LDL (HMG-CoA reductase)
AE: Hepatotoxicity, rhabdomyolysis

Question 3

Cholestyramine MOA

Answer 3

Increased bile production to promote cholesterol excretion

Question 4

Ezetimibe MOA, CI

Answer 4

Decrease cholesterol absorption
Pregnancy

Question 5

Gemfibrozil MOA AE

Answer 5

Break down of fat, decrease production of triglycerides
Gi upset, myopathy, hepatotoxicity

Question 6

Niacin MOA AE

Answer 6

Blocks fat breakdown, decrease triglycerides and LDL
AE: Myopathy, diarrhea, Reduced vitamins ADEK

Question 7

Heart failure treatment meds

Answer 7

Digoxin
Milrinone

Question 8

Digoxin Class, MOA

Answer 8

Cardiac glycoside (only one in US)
positive inotrope
Inhibits Na/K pump

Question 9

Digoxin Indication, AE

Answer 9

Decreased cardiac output, heart failure, atrial fibrillation
V fib, bradycardia, dizziness

Question 10

Digoxin toxicity Cause, S/S

Answer 10

Cause: hypokalemia
S/S: confusion, loss of appetite, n/v visual disturbances,

Question 11

Milrinone MOA, I, AE

Answer 11

Increase contractility
Acute heart failure
V fib, headache

Question 12

Adenosine MOA, I, AE

Answer 12

Heart reset
Supraventricular tachycardia
impending doom

Question 13

Amiodarone I, AE

Answer 13

Cardiac dysrhythmias, recurrent v fib
Hypotension, visual changes, blue skin

Question 14

Atenolol/metoprolol MOA, I

Answer 14

B1 blocker
HTN, angina, heart failure, post MI
Black box warning

Question 15

Captopril MOA, AE

Answer 15

ACE inhibitor (angiotensin II reduction)
Dry Cough

Question 16

Losartan MOA,

Answer 16

Blocks Angiotensin II receptors
Reduced chance of cough

Question 17

ACE inhibitors and Common AE, CI,

Answer 17

Captopril, LIsinopril
hyperkalemia, angioedema, cough
Renal injury, pregnancy

Question 18

Nifedipine/amlodipine MOA, I, AE

Answer 18

Calcium channel blocker in smooth muscle and arteries
HTN
Vasodilation, constipation

Question 19

Verapamil/diltiazem MOA, I, AE

Answer 19

Calcium channel blocker, decrease heart contractility and rate
Afib, angina, HTN
Constipation, Hypotension

Question 20

Nitroglycerin I and special

Answer 20

Angina, HTN
Can develop tolerance, 12 hr cycle

Question 21

Ranolazine MOA, i, AE

Answer 21

Lowers cardiac oxygen demand
stable angina
QT prolongation

Question 22

Procainamide MOA, I , AE

Answer 22

Blocks sodium channel
VTachy, supraventricular tachy, a fib
hypotension wide QRS