Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Module 7 (Critical Care) > Exam 4 Pharmacology > Flashcards

Exam 4 Pharmacology Flashcards

Naloxone, Flumazenil, Gabapentin, Ketorolac, Methotrexate, Lorazepam, Levofloxacin, Haloperidol

1
Q

Naloxone MOA

A

opioid antagonist
- reverses the effects of opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Naloxone is used for

A

rapidly reversing opioid overdose
- heroin, morphine, and oxycodone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Naloxone side effects

A

acute opioid withdrawal
- pain, tachycardia, HTN, fever, sweating, abd cramps, N/V/D, agitation and irritability
combative
injection site reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Naloxone side effects - neonate

A

acute opioid withdrawal from mothers with opioid dependence
- excessive crying
- shrill cry
- failure to feed
- seizures
- hyperactive reflexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Naloxone adverse effects

A
  • flushing, BP instability, presyncope, VTach and VFib
  • hot flash
  • increase serum bilirubin
  • hallucinations
  • withdrawal syndrome
  • hypoxia
  • pulmonary edema
  • VTach and VFib
  • pulmonary depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Naloxone nursing interventions/assessments

A

Monitor for AMS, respiratory depression, and shock
(Neuro and pulmonary)
- Naloxone has a shorter half-life than the opioids
- pulse Ox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Naloxone contraindications/precautions

A

cardiovascular disease
- hypotension
- pulmonary edema
- arrythmias
- instability = ventricular fibrillation
seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Naloxone drug type

A

Opioid Antagonist (Antidote)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Naloxone related with Opioid ODs

A

Naloxone has a shorter half-life than the opioids
may need to give the antidote more than once

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Naloxone routes

A

IN
IM
IV
ETT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Naloxone acts within

A

normal breathing 2-5 minutes
- if not responding give another dose
- rescue breathing while waiting for effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Naloxone wears off within

A

30-90 minutes following admin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Flumazenil MOA

A

binds to extracellular GABA receptors and prevents benzo molecules from binding
- reverses on CNS system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Flumazenil is used for

A

antidote for Benzodiazepines for a sedative
- Valium
- Versed
- Xanax
Tranxene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Flumazenil side effects

A

HA
N/V
dizzy
increased sweating
flushing (sudden warmth, redness, or tingly feeling)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Flumazenil adverse effects

A

cardiac arrythmias
rapid, pounding pulse
seizures
respiratory depression
ongoing drowsiness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Flumazenil nursing interventions/assessments

A

seizure precautions
monitor respiratory status
CNS depression
amnesia or resedation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Flumazenil contraindications

A

unknown or mixed OD
tolerance
seizure disorders
prolonged QRS interval

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Flumazenil generic name

A

Romazicon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Flumazenil drug type

A

Benzo antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Flumazenil routes

A

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Gabapentin MOA

A

crosses lipid membrane barriers on the amino aid transportation
- GABA synthetic enzyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Gabapentin is used for

A

Tx epilepsy
nerve pain (diabetes and shingles)
Cerebral palsy shakes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Gabapentin side effects

A

sleepy, dizzy
N/V/D
mood changes
swollen extremities
blurred vision
dry mouth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Gabapentin adverse effects

A

CNS and respiratory depression
aggression, hyperkinetic muscle activity
suicidal ideation and tendencies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Gabapentin nursing interventions/assessments

A

LOC, mental health
hx of depression and ideation
- seizure precautions
- infection control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Gabapentin drug type

A

Anticonvulsant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Gabapentin routes

A

PO
- same time each day

29
Q

Ketorolac MOA

A

inhibits prostaglandin synthesis by blocking COX enzyme

30
Q

Ketorolac is used for

A

moderate to severe pain after an operation
- NSAIDs
- short term

31
Q

Ketorolac side effects

A

stomach cramp, burn, gas, bloating
constipation

32
Q

Ketorolac adverse effects

A

GI bleed to ulcers
CV thombosis
CVA, MI, HTN

33
Q

Ketorolac contraindicated in

A

renal impairment
- CRRT
heparin therapy

34
Q

Ketorolac labs

A

Platelets
PT/INR

35
Q

Ketorolac nursing interventions/assessments

A

with PPI to help with peptic ulcer
FALL RISK
MONITOR LFT

36
Q

Ketorolac drug type

A

NSAID after operation

37
Q

Ketorolac routes

A

PO, NASAL, IV, IM

38
Q

Methotrexate MOA

A

prevents nitric oxide sythese and increase sensitivity to T cells apoptosis
- getting rid of immune responses

39
Q

Methotrexate drug type

A

Antimetaolite

40
Q

Methotrexate is used for

A

RA
Psoriasis
CA

41
Q

Methotrexate side effects

A

cough
HA
diarrhea
dizzy
nausea,vomiting
chills

42
Q

Methotrexate adverse effects

A

bone marrow suppression
serious infections
renal, GI, liver, pulmonary impairment
loss of child if pregnant

43
Q

Methotrexate labs

A

WBCs
platelets
LFTs
Cr and BUN

44
Q

Methotrexate nursing interventions/assessments

A

watch for bleeding
no diuretics or NSAIDs
ASSESS BUCCAL FRO DRYNESS
MONITOR FOR INFECTIONS AND SKIN REACTIONS
- rinse mouth with water, contraceptives, flush twice

45
Q

Methotrexate routes

A

PO, SQ, IM

46
Q

Lorazepam MOA

A

binds to benzo receptors on GABA channel for CNS depression

47
Q

Lorazepam drug types

A

Benzodiazepines

48
Q

Lorazepam is used for

A

anxiety short term
sleeping

49
Q

Lorazepam side effects

A

confusion
blurry
dizzy
dark urine
constipation

50
Q

Lorazepam adverse effects

A

respiratory depression
risk of suicidal ideation, depression, and hallucinations

51
Q

Lorazepam labs

A

CBC, liver function tests, and LDH
glycol toxicity, serum creatinine, BUN, serum lactate, and osmolality gap.

52
Q

Lorazepam nursing interventions/assessments

A

seizure/fall precautions
dilute

double check with others

53
Q

Lorazepam routes

A

IV

54
Q

Levofloxacin MOA

A

direct inhibits bacterial DNA synthesis

55
Q

Levofloxacin drug type

A

Antibiotic of the fluroquinolones

56
Q

Levofloxacin is used for

A

Bacterial infections (nosocomial pneumonia to UTIs)
- Anthrax
- Plague

57
Q

Levofloxacin side effects

A

HA
diarrhea
abd gas
seizures
pain
irregular heart beat

58
Q

Levofloxacin adverse effects

A

inflammation or tearng of tendons
- bruise easy
black tarry stools
unusual wt gain
hepatitis

59
Q

Levofloxacin labs

A

I&Os
LFTs

60
Q

Levofloxacin nursing interventions/assessments

A

neuro
WBCs
signs of infection
cystalluria
drink plenty of water

61
Q

Levofloxacin routes

A

PO, IV

62
Q

Haloperidol MOA

A

block dopamine receptors

63
Q

Haloperidol drug type

A

1ST gen typical antipsychotic

64
Q

Haloperidol is used for

A

Tx nervous, emotional and mental (Schizophrenia)
Tourettes
dementia behavioral problems

65
Q

Haloperidol side effects

A

drowsy, dizzy
fast pulse
blurry vision
anticholinergic
increased temp
urinary retention and constipation

66
Q

Haloperidol adverse effects

A

stiff neck - EPS
wt gain
erectile dysfunction
amenorrhea
sedation
NMS

67
Q

Haloperidol labs

A

ECG
VS - orthostatic hypotension

68
Q

Haloperidol nursing interventions/assessments

A

neuro
seizure and EPS (muscle twitch and exorcisms)
VS
NMS - fluctuations in BP and pulse, loc, hyperthermia and rigid

69
Q

Haloperidol routes

A

IM, IV

Module 7 (Critical Care) (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions