Exam 4: heart failure Flashcards
what is heart failure?
- a cardiovascular condition
- heart is unable to pump an adequate amount of blood to meet the metabolic needs of the body’s tissues
how is heart failure characterized?
- left ventricular dysfunction
- reduced exercise tolerance
- diminished quality of life
- shortened life expectancy
what are the 7 risk factors of heart failure?
- CAD
- advancing age
- HTN
- DM
- tobacco use
- obesity
- high cholesterol levels
what is the etiology of heart failure?
any interference with the normal mechanisms regulating cardiac output
what are the 4 mechanisms that regulate cardiac output?
- preload
- afterload
- myocardial contractility
- heart rate
what are the 9 precipitating factors of heart failure?
- anemia
- infection
- thyrotoxicosis
- hypothyroidism
- arrhythmias
- bacterial endocarditis
- pulmonary disease
- nutritional deficiencies
- hypervolemia
what is systolic failure? what is this aka? what does this cause?
- a defect in the ability of the cardiac myofibrils to shorten
- HFeEF
- causes a decrease in the muscles ability to contract (pump)
how is systolic failure characterized? who experiences this more often?
low forward blood volume
men
what are the 4 causes of systolic failure?
- impaired contractile function
- increased afterload
- cardiomyopathy
- mechanical abnormalities
how is diastolic failure characterized? what is it aka? who experiences this more often?
- high filling pressures
- venous engorgement in both pulmonary and systemic systems
- HFpEF (heart failure with preserved ejection fraction
- women
how is mixed failure characterized?
- low blood pressure
- low CO
- poor renal perfusion
what are the 5 compensatory mechanism for heart failure?
- SNS activation
- neurohormonal response
- ventricular remodeling
- dilation/hypertrophy
- natriuretic petides
how does SNS activation compensate for heart failure? when does this happen?
- release of catecholamines
- increase heart rate
- increase myocardial contractility
- peripheral vasoconstriction
- first thing that happens
- works but after awhile, the heart overworks itself and it ends up detrimental
how do neurohormonal responses compensate for heart failure?
- RAAS
- low CO causes a decrease in cerebral perfusion pressure, ADH is released
- arterial vasoconstriction
- increased contractility
- hypertrophy
what effect does a pro-inflammatory cytokines release have on the heart?
- depressed cardiac function
- over time, cardiac wasting, muscle myopathy, and fatigue
what triggers natriuretic peptides to be released? what effect do these have on the heart?
- released in response to atrial volume and ventricular pressure
- promotes venous and arterial vasodilation
- enhances diuresis
- blocks effects of RAAS
- may have inflammatory effects
what does nitrous oxide do for the heart?
relaxes arterial smooth muscle, resulting in vasodilation and decreased afterload
what is left sided heart failure?
increased blood in the left atrium and pulmonary vein
what is right sided heart failure?
back flow of blood into the right atria and venous circulation
s/s of left sided heart failure?
fatigue paroxysmal noturnal dyspnea orthopnea tachycardia restlessness confusion exertional dyspnea cyanosis increased pulmonary capillary wedge pressure pulmonary congestion
s/s of right sided heart failure?
may be secondary distended jugular veins anorexia GI distress weight gain dependent edema fatigue hepatomegaly splenomegaly increased peripheral venous pressure ascites
s/s of pulmonary congestion?
cough crackles wheezing bloody sputum tachypnea
s/s pf acute decompensated HF?
fatigue dyspnea tachycardia edema nocturia skin changes behavior changes chest pains weight changes
how many classes of persons with HF are there?
4
at diagnosis of heart failure, the pt knows that they have what percent chance of being alive in 5 years?
50%