Exam 4

Question 1

Important 1st steps in diagnosis of anemia

Answer 1

Patients history, physical exam, and Cbc with indices

Question 2

– and – are often seen when anisocytosis is present

Answer 2

Microcytes and macrocytes

Question 3

Important contributors to the development of anemia

Answer 3

Increased rbc destruction and decreased rbc production

Question 4

Caused by defective function of the hematopoietic stem cell

Answer 4

Sideroblastic anemia

Question 5

Often seen in patients exhibiting extra vascular hemolysis

Answer 5

Spherocyte

Question 6

Leads to anemia upon exposure to drugs or reagents causing hemolysis

Answer 6

G6PD deficiency

Question 7

What condition is present if schistocytes (helmet cells) are seen?

Answer 7

Erythrocyte Hemolysis

Intravascular hemolysis

Question 8

Significance of an increased rdw?

Answer 8

Lab diagnosis of hemoglobin

Question 9

Defective Dna synthesis is important factor in

Answer 9

Megaloblastic anemia

Question 10

Where is most iron of the body found?

Answer 10

In the hemoglobin

Question 11

Pancytopenia definition

Answer 11

deficiency of all three cellular components of the blood (red cells, white cells, and platelets).

Question 12

Poikilocytosis Definition

Answer 12

Abnormal sized shaped rbc. Teardrops

Question 13

The physiologic cause of megaloblastic anemia

Answer 13

Macrocytic anemia, defective b12 utilization

Question 14

Role of b12 and folic acid in the body

Answer 14

B12- Helps keep the blood, nerves, anemia all healthy in the body
F. Acid- up keeps the brain

Question 15

Significance of donath-lansteiner antibody

Answer 15

immunoglobulins formed in response to a viral, bacterial, or spirochete infection and are capable of inducing Paroxysmal Cold Hemoglobinuria (PCH), an autoimmune hemolytic anemia

Question 16

Causes most cases of acquired aplastic anemia?

Answer 16

rare, serious blood disorder, due to failure of the bone marrow failure to produce blood cells.