Exam 2 Notes Flashcards
Different hemoglobin structure
A2, F, A
What organ is responsible for removal of aged rbc?
Spleen
Largest organs for iron storage
Liver & spleen
Earliest identifying cell is call a
Myloblast
Granucytes that’s associated w allergies
Eosinphils
Lymphocytes can be produced at what locations?
Thymus gland, spleen, bone marrow
What happens to WBC nucleus as it matures?
Nucleus starts to become more condensed/clumping
Major proteins can transfer and carry iron?
Transperitin
With a iron overload you use a
Prussian blue stain
What’s not found in adults?
Gower 1 and Gower 2 (early embryogenesis )
Composition of hemoglobin
2 alpha chains, 2 beta chains
CBC is
Free counting of circulating cells through the blood
Cells that produce antibodies
Plasma cells
B cells
NormAl ranges for hemoglobin
Males 14-18 g/dl
Females 12-15 g/dl
Newborn 16.5-21.5 g/dl
Methemoglobin is a —type of hemoglobin
Hemoglobin in which iron is in the oxidized ferric Fe3+ state and unable to bind oxygen
Heme is a compound based on
Protoporphyrin IX( 9 )
Heme is produced
In the bone marrow
Caroxyhemoglobin is
Hub bound to carbon monoxide
Deoxyhemoglobin is
Hbg without bound oxygen
Oxyhemoglobin is
Hgb bound to oxygen
Hemoglobins present at birth
(HgB F) - 2 Alpha + 2 Gamma + 4 Heme = fetal Hgb
Kind of cell CD4 is
CD4 is a helper T cell
Kind of cell CD8 is
A cytotoxic T cell
Clinical condition for neutrophilia
Smoking, disorders, Bacterial/parasitic/fungal infections
Clinical condition for lymphocytosis
High lymphocyte count. Infection(bacterial/fungal), cancer of the blood, hiv
Clinical condition for eosinophilia
High levels of Eosinphils.
Destroying foreign substances and regulating inflammation
Is here is most of iron located in the body?
70% of iron is found in rbc(hemoglobin). Also in muscle cells(myoglobin)
Hemoglobin A1C
Uncontrollable diabetes
