Exam 2 Notes Flashcards

1
Q

Different hemoglobin structure

A

A2, F, A

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2
Q

What organ is responsible for removal of aged rbc?

A

Spleen

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3
Q

Largest organs for iron storage

A

Liver & spleen

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4
Q

Earliest identifying cell is call a

A

Myloblast

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5
Q

Granucytes that’s associated w allergies

A

Eosinphils

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6
Q

Lymphocytes can be produced at what locations?

A

Thymus gland, spleen, bone marrow

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7
Q

What happens to WBC nucleus as it matures?

A

Nucleus starts to become more condensed/clumping

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8
Q

Major proteins can transfer and carry iron?

A

Transperitin

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9
Q

With a iron overload you use a

A

Prussian blue stain

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10
Q

What’s not found in adults?

A

Gower 1 and Gower 2 (early embryogenesis )

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11
Q

Composition of hemoglobin

A

2 alpha chains, 2 beta chains

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12
Q

CBC is

A

Free counting of circulating cells through the blood

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13
Q

Cells that produce antibodies

A

Plasma cells

B cells

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14
Q

NormAl ranges for hemoglobin

A

Males 14-18 g/dl
Females 12-15 g/dl
Newborn 16.5-21.5 g/dl

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15
Q

Methemoglobin is a —type of hemoglobin

A

Hemoglobin in which iron is in the oxidized ferric Fe3+ state and unable to bind oxygen

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16
Q

Heme is a compound based on

A

Protoporphyrin IX( 9 )

17
Q

Heme is produced

A

In the bone marrow

18
Q

Caroxyhemoglobin is

A

Hub bound to carbon monoxide

19
Q

Deoxyhemoglobin is

A

Hbg without bound oxygen

20
Q

Oxyhemoglobin is

A

Hgb bound to oxygen

21
Q

Hemoglobins present at birth

A

(HgB F) - 2 Alpha + 2 Gamma + 4 Heme = fetal Hgb

22
Q

Kind of cell CD4 is

A

CD4 is a helper T cell

23
Q

Kind of cell CD8 is

A

A cytotoxic T cell

24
Q

Clinical condition for neutrophilia

A

Smoking, disorders, Bacterial/parasitic/fungal infections

25
Q

Clinical condition for lymphocytosis

A

High lymphocyte count. Infection(bacterial/fungal), cancer of the blood, hiv

26
Q

Clinical condition for eosinophilia

A

High levels of Eosinphils.

Destroying foreign substances and regulating inflammation

27
Q

Is here is most of iron located in the body?

A

70% of iron is found in rbc(hemoglobin). Also in muscle cells(myoglobin)

28
Q

Hemoglobin A1C

A

Uncontrollable diabetes