EXAM 4 Flashcards
GIT
A 71-year old man with a long history of alcohol-related liver cirrhosis showed a subtlebut equivocal area of abnormality on a screening ultrasound. His AFP was raised at 2,000.An MRI of the liver with contrast is performed. All of the following are expected featuresof infiltrative HCC on MRI, except
A. Hyperintense on MR images acquired during the hepatobiliary phase after injection ofhepatocyte-specific contrast agent.
B. A reticular appearance of the tumour can be seen during the venous and equilibriumphase.
C. Washout appearance of the tumour is usually reported as irregular andheterogeneous.
D. Infiltrative HCC may commonly appear as iso- or hypointense on images obtainedduring the arterial phase.
E. Infiltrative HCC may be difficult to discern from underlying heterogeneous cirrhosisbecause of its permeative appearance.
A. Hyperintense on MR images acquired during the hepatobiliary phase after injection of hepatocytes specific contrast agent
At contrast-enhanced CT and MR imaging, infiltrative HCC may be difficult to discern from underlying heterogeneous cirrhosis because of its permeative appearance, its minimal and inconsistent arterial enhancement and the heterogeneous washout appearance that occurs during the venous phase. The enhancement pattern of infiltrative HCC seen on images obtained during the hepatic arterial phase has been reported as minimal, patchy or miliary.
Although arterial hyperenhancement is a key diagnostic feature of nodular and massive HCC, infiltrative HCC may commonly appear as iso- or hypointense on images obtained during the arterial phase. Washout appearance is a specific CT and MR imaging feature of typical nodular HCC. Hypointensity relative to the surrounding liver parenchyma during the venous phase of enhancement remains a valid sign for the detection of infiltrative HCC. However, washout appearance of the tumour is usually reported as irregular and heterogeneous and is less frequently seen in infiltrative HCC than in other HCC subtypes.
Moreover, a reticular appearance of the tumour has been seen on images obtained during the venous and equilibrium phases, possibly related to fibrosis. Finally, the tumour generally appears as hypointense on MR images acquired during the hepatobiliary phase after injection of hepatocyte specific contrast agent because of the lack of contrast agent uptake.
CHEST
Which of the following is false?
A. NSIP ——- Scleroderma
B. Sjögren’s syndrome ——- Lymphocytic interstitial pneumonitis (LIP)
C. Lofgren’s syndrome ——- Systemic lupus erythematosus (SLE)
D. Loeffler’s syndrome ——- Acute eosinophilia
E. Folded lungs ——- Asbestosis
GU
Which one of the following statements regarding the testes is false?
A. Tubular ectasia of the testis is a benign condition.
B. Undescended testes are most commonly found in the inguinal canal.
C. Metastases are most commonly from prostate and lung primary.
D. Testicular cysts are mostly incidental and non-palpable.
E. Sertoli cell tumour is the most common malignant testicular tumour.
MSK
A 21-year-old woman attends the A&E department with acute onset of pain in the right upperarm with limitation of mobility. The plain radiograph report describes a ‘fallen fragment’ sign.Which one of the following bony lesions does this finding refer to?
A. Giant cell tumour
B. Simple bone cyst
C. Eosinophilic granuloma
D. Aneurysmal bone cyst
E. Benign cortical defect
CNS
A 43-year-old patient with known diagnosis of AIDS presented with ataxia and progressive neurological deficits. MRI brain revealed patchy high signal on T2W images in the parieto occipital white matter. No mass effect or contrast enhancement was evident What is the diagnosis?
A. Primary CNS lymphoma
B. AIDS dementia complex
C. Progressive multifocal leukoencephalopathy
D. Periventricular leukomalacia
E. Encephalitis
CHEST
A 6-year-old with spina bifida has a chest X-ray performed for possible lower respiratory tract infection. The lungs are clear but there is a well-defined, round paraspinal mass with an air-fluid level. What is the most likely diagnosis?
A. Bronchogenic cyst
B. Morgagni hernia
C. Oesophageal duplication cyst
D. Cystic teratoma
E. Oesophageal tumour
GIT
A 77-year-old man with weight loss and deranged LFTs had an ultrasound scan that showed multiple liver lesions suspicious for metastases. Contrast-enhanced CT of the chest and abdomen was done in search of the primary’. Which one of the following is the most common primary tumour that has hypovascular liver metastases?
A. Pancreas
B. Stomach
C. Colon
D. Kidney
E. Melanoma
CHEST
A 65-year-old woman is recovering from a double lung transplant On the fourth day post-transplant, she starts complaining of shortness of breath. Clinical findings include some basal crackles; air entry seems satisfactory in the upper zones. An urgent chest X-ray is organised. Portable up-to-date chest X-ray shows evidence of pulmonary’ oedema. What is the most likely cause for this appearance?
A. Barotrauma
B. Acute graft failure
C. Volume overload
D. Response to antirejection treatment
E. Reimplantation response
GU
Cryptorchidism has an increased risk of development of all of the following testicular tumours, except
A. Leydig cell tumour
B. Seminoma
C. Yolk sac tumour
D. Embryonal cell tumour
E. Choriocarcinoma
MSK
A 15-year-old teenager presents with a worsening pain in his right ankle. He is an active sports player and plays football for the school club. A radiograph reveals an undisplaced fragment in the medial aspect of the talar dome with a small lucent line around it.
All of the following are well-recognised locations for osteochondral lesions or defects, except
A. Lateral aspect of the medial femoral condyle
B. Medial aspect of the talar dome
C. Lateral aspect of the medial tibial plateau
D. Anterior aspect of the capitellum
E. Humeral head
CNS
A 35-year-old woman with pre-eclampsia underwent a CT of the brain to exclude intracranial haemorrhage. The CT revealed low attenuation in the white matter of the posterior aspect of both cerebral hemispheres. The abnormal area appeared low on T1W and high on T2W images and was isointense on DWI. No contrast enhancement was evident. What is the diagnosis?
A. Periventricular leukomalacia
B. Progressive multifocal leukoencephalopathy
C. Encephalitis
D. Reversible posterior leukoencephalopathy syndrome
E. CNS lymphoma
CHEST
A male infant is bom at 39 + 3 weeks gestation. Prenatal ultrasound demonstrated a partly cystic, partly echogenic mass in the right upper lobe. Shortly after delivery the infant is in respiratory distress. Initial chest X-ray demonstrates dense lungs bilaterally with increased volume on the right. On Day 2, a repeat chest X-ray demonstrates multiple air-filled cystic masses of varying sizes within the right upper lobe with mediastinal shift to the left. What is the most likely diagnosis?
A. Bronchogenic cyst
B. Morgagni hernia
C. Congenital cystic adenomatoid malformation
D. Congenital lobar emphysema
E. Hyaline membrane disease
GIT
A 78-vear-old woman with worsening right upper quadrant pain and worsening obstructive liver function test has a CT scan that shows a heterogeneous mass in the peripheral aspect of the liver with capsular retraction and segmental biliary duct dilatation proximal to the mass. There is no prior history of chronic Ever disease. What is the most likely diagnosis?
A. HCC
B. Siderotic nodule
C. Adenoma
D. Cholangiocarcinoma
E. Angiosarcoma
CHEST
A 36 year old immunocompromised woman with a knowm history of gestational trophoblastic disease showed bilateral bronchopneumonic infiltrates on chest X-ray.
An HRCT was suggested for further characterisation. The HRCT showed several areas of ground glass change surrounded by a rim of consolidation. The differential diagnosis for these findings would include all of the following, except
A. Wegner s granulomatosis
B. Invasive pulmonary aspergillosis
C. Choriocarcinoma metastasis
D. Sarcoidosis
E. Lymphangioleiomyomatosis
GU
Enhanced CT scan of an otherwise healthy motor vehicle accident victim demonstrates no enhancement of the right kidney on Day 0. A repeat contrast-enhanced CT scan obtained on Day 3 demonstrates a thin marginal rim of subcapsular enhancement of uniform thickness, described as the rim sign. The collecting system was mildly prominent. What is the most likely explanation?
A. Analgesic overuse
B. Renovascular compromise
C. Diabetes mellitus
D. Pyelonephritis
E. Developing hydronephrosis
MSK
A 44-year-old man presents with increasingly severe and disabling pain in the left inguinal and anterior thigh region. The pain is exacerbated by weight-bearing and relieved by rest. The patient mentions that the pain began 2 months ago, was acute in onset, and there was no preceding trauma. A radiograph of his left hip reveals a focal osteopaenic region within the left femoral head; this is no longer evident on a follow-up film 8 months later. Which of the following is the most likely diagnosis?
A. Osteomalacia
B. Avascular necrosis
C. Transient osteonecrosis
D. Transient osteoporosis
E. Occult fracture
CNS
A 35-year old woman with bilateral facial nerve palsy showed extensive nodular deposits with diffuse enhancement of the meninges on CECT of the brain. Which of the following imaging investigation will likely confirm the diagnosis?
A. MR angiogram of the circle of Willis
B. Ultrasound of the liver
C. Intravenous urogram
D. Plain chest radiograph
E. Plain radiograph of both hands
CHEST
A 10-month-old infant attends the local infectious diseases unit with his mother who recently emigrated from Zimbabwe. The child has shortness of breath, fever and bilateral inspiratory crackles. Chest X ray demonstrates diffuse bilateral ground-glass opacification. What is the most likely diagnosis?
A. Varicella pneumonia
B. Round pneumonia
C. Pneumocystis pneumonia (PCP)
D. Bronchopulmonary dysplasia
E. Congestive cardiac failure
GIT
A 65-year old hepatitis C-positive man is found to have a liver mass on screening ultrasound. A suspicion of HCC was raised. Which one of the following statements regarding HCC screening is false?
A. HCC is characteristically hyperechoic on ultrasound.
B. The majority of nodules that measure less than 1 cm are not HCC.
C. It develops in a background of preexisting liver parenchymal damage.
D. HCC is commonly diagnosed on the basis of imaging features alone, without histologic confirmation.
E. The nodules that are suspicious for HCC are new nodules that measure more than 1 cm or nodules that enlarge over a time interval.
CHEST
A 42-year-old factory worker complains of chest tightness and shortness of breath during the early days of the week, settling down during the weekend over the last several months.
Chest radiograph is normal. HRCT is requested for further evaluation. What do you expect the HRCT to show?
A. Crazy paving pattern
B. Patchy ground-glass opacities with centrilobular nodules
C. Perilymphatic nodules with beaded fissures
D. Central bronchiectasis
E. Extensive mediastinal and hilar lymphadenopathy
GU
A CT scan, obtained in a patient with haematuria after minimal trauma, reveals a rim of enhancement surrounding a markedly dilated right renal pelvis and collecting system. Note is made of variable thickness to the enhancing rim and enhancing cortical strands. The report describes it as a rim sign. What is the likely diagnosis?
A. Hydronephrosis
B. Renovascular compromise
C. Diabetes mellitus
D. Pyelonephritis
E. Fractured kidney
CNS
In the case of a vertebral compression fracture, all the statements regarding imaging findings suggests a malignant cause, except
A. Involvement of the posterior elements
B. Persistent loss of T1W bone marrow signal on sequential imaging
C. Paravertebral soft-tissue component
D. Post-contrast gadolinium enhancement
E. Convex posterior border of the vertebral body
CNS
All of the following are true of toxoplasmosis of AIDS, except
A. It is the most common focal CNS infection.
B. Treatment is started empirically based on imaging.
C. The basal ganglia and cerebral hemispheres are commonly involved.
D. Haemorrhage and calcification are common post-therapy.
E . A single lesion is the most common.
CNS
On newborn heel stick screening, a newborn infant is found to suffer from congenital hypothyroidism. On ultrasound, the thyroid gland is diffusely enlarged, and on Technetium 99m thyroid scintigraphy there is increased uptake of radioactive tracer within the gland. There is no evidence of ectopic thyroid tissue.
What is the most likely cause for the congenital hypothyroidism?
A. Thyroid hypoplasia
B. Hypothalamic dysfunction
C. Thyroid dyshormonogenesis
D. Maternal antibody induced hypothyroidism
E. Hypopituitarism
GIT
An 8-year-old child with right upper-abdominal pain and a palpable mass was sent for US of the liver. The US showed a large heterogeneous mass occupying at least half of the right lobe of the liver. The rest of the liver was normal in appearance. Which one of the following is the most common benign primary liver tumour in children?
A. Hepatocellular carcinoma
B. Hepatoblastoma
C. Angiosarcoma
D. Infantile haemangioendothelioma
E. Cholangiocarcinoma
CNS
A 43-year-old woman with history of proteinuria presented to the A&E department with shortness of breath and haemoptysis. Chest X-ray showed diffuse airspace opacities and an HRCT was organised. The HRCT showed diffuse airspace opacities, ground-glass change and confluent consolidation, which was reported as acute diffuse alveolar haemorrhage. Which of the following can be classically expected on CT sinus study?
A. Bilateral frontal mucocoele
B. Unilateral sinusitis involving all the sinuses on one side
C. Chronic destructive sinusitis with nasal perforation
D. Hypoplastic maxillary sinuses
E. Oro-antral fistula
GU
A CT scan, obtained to exclude retroperitoneal hematoma in a patient with sustained hypotension for 1 hour after cardiac catheterisation and subsequent cardiac arrest, shows a hypoattenuating renal cortex compared with the medullary enhancement No additional contrast material was given at the time of the CT. Which of the following signs is being described here?
A. Hydronephrotic rim sign
B. Comet tail sign
C. Crescent sign
D. Reverse rim sign
E. Soft-tissue rim sign
MSK
A report is issued stating that there is a periosteal reaction associated with what the radiologist believes is a benign bony lesion. What type of periosteal reaction is most likely to be associated with a benign lesion?
A. Codman
B. Sunburst
C. Hair-on-end
D. Lamination
E. Buttressing
CNS
All of the following are associated with tuberous sclerosis, except
A. Giant cell astrocytoma
B. Subependymal hamartomas
C. Pheochromocytoma
D. Cardiac rhabdomyoma
E. Chylothorax
GIT
A 22-month-old boy presents with abdominal pain and is found on US to have an intussusception.
Which of the following statements is false with regard to his initial management and treatment?
A. The patient should be reviewed for signs of peritonitis by a paediatric surgeon.
B. Bowel infarct, peritonitis and perforation are potential complications if the intussusception is left untreated.
C. The patient should be fluid resuscitated prior to attempts at air enema reduction.
D. A plain abdominal radiograph should be obtained prior to air enema reduction to rule out signs of perforation.
E. A successful intussusception reduction is noted when air is seen to fill the small bowel loops.
GIT
An MRI of the liver with contrast was performed in a 50-year-old woman after a complex mass was identified on US. The mass was reported as suspicious for epithelioid haemangioendothelioma. All of the following are expected features of this lesion, except
A. Vascular origin
B. Female predominance
C. Typical presentation of multifocal nodules
D. Avid arterial phase enhancement
E. Capsular retraction
CHEST
A 37-year-old woman with asthma underwent HRCT of the chest and was diagnosed based on clinical examination, blood tests and HRCT to have Churg-Strauss syndrome or allergic granulomatosis. Which of the following appearances would fit with
the diagnosis?
A. Peripheral predominant lobular consolidation with centrilobular nodules
B. Peripheral predominant homogenous consolidation without centrilobular nodules
C. Peripheral predominant interstitial reticular opacities with underlying traction bronchiectasis
D. Central bronchiectasis and patchy airspace opacities with mucous plugs
E. Upper lobe predominant interstitial pulmonary fibrosis with architectural distortion
GU
Which of the following is incorrect?
A. Spoke wheel sign —– Renal oncocytoma
B. Pear-shaped bladder sign —– Pelvis lipomatosis
C. Pie-in-the-sky bladder sign —– Bilateral psoas hypertrophy
D. Spaghetti sign —– Haematuria
E. Balloon-on-a-string sign —– Hydronephrosis
MSK
A young adult man presents with a painful left wrist following a fall from height. A lateral view of the wrist shows loss of co linearity of the radius/lunate/capitate axis with the capitate displaced dorsally. What injury is this constellation of findings compatible with?
A. Midcarpal dislocation
B. Perilunate dislocation
C. Lunate dislocation
D. Volar intercalated segmental instability
E. Dorsal intercalated segmental instability
CNS
All the following are true of venous angioma, except
A. It can be considered normal.
B. It contains small arterial channels.
C. It is associated with cavernomas.
D. It shows a spoked wheel configuration on imaging.
E. It normally has a large draining vein but no feeding arteries.
CHEST
A 5-year old boy, who underwent a bone marrow transplantation 1 week earlier for an underlying haematological malignancy, presents with shortness of breath, cough and chest tightness.
Which of the following complications would be least likely?
A. Lymphoid interstitial pneumonitis
B. Pulmonary oedema
C. Pulmonary embolism
D. Infective interstitial pneumonitis from CMV
E. Idiopathic interstitial pneumonitis
GIT
A 56-year-old woman presented to her GP with pain and palpable mass in the right upper quadrant. She was sent for US, which showed a large heterogeneous mass in the right lobe of the liver. A contrast-enhanced MRI of the liver is urgently organised for further characterisation. The lesion is reported as consistent with fibrolamellar carcinoma.
All of the following are expected findings, except
A. Central scar low on T1W and T2W images.
B. Solitary mass is the usual presentation.
C. Favorable prognosis.
I). Rare pathological subtype of hepatocellular carcinoma.
E. Background cirrhotic change to the liver parenchyma.
CVS
A 37-year-old woman involved in a frontal car collision and collapse at the scene of incident was brought to the A&E department and sent for an emergency whole-body CT. All of the following are correct regarding blunt cardiac trauma, except
A. Cardiac concussion results in abnormal cardiac enzymes.
B. Traumatic pericardial rupture resulting from blunt chest trauma is rare.
C. Cardiac herniation is a serious complication of pericardial rupture.
D. Traumatic ventricular septal defects affect the muscular portion.
E. Myocardial contusion is associated with cardiac tamponade.
GU
An 88-year-old man with obstructive uropathy and hard nodular prostate gland on digital rectal examination was being further investigated for his prostate cancer. Which one of the following magnetic resonance spectroscopic imaging metabolic peaks is expected in a patient with prostate cancer?
A. High citrate peak, low choline/creatine peak
B. High citrate peak, high choline/creatine peak
C. Low citrate peak, high choline/creatine peak
D. Low citrate peak, low choline/creatine peak
E. Low citrate peak, normal choline/creatine peak
MSK
A 42-year old woman with knee joint stiffness, pain and reduced mobility is investigated with a plain X-ray, which reveals extensive soft-tissue swelling around the joint with
large periarticular erosions. There is no evidence of calcification and bone density is maintained. MRI shows low-signal foci within the soft-tissue mass. What is the likely diagnosis?
A. Pigmented villonodular synovitis
B. Haemophilia
C. Synovial sarcoma
D. Behcet’s syndrome
E. Psoriatic arthropathy
CNS
A 40-year-old woman with progressive difficulty in walking and difficulty in holding objects reveals a large burn over the dorsum of her right hand on clinical examination. Sagittal MRI of the cervical spine shows a long segment lesion in the cervical and upper thoracic spinal cord with low signal on T1W images and high signal on T2W images without
any change on post-contrast images. What is the diagnosis?
A. Ependymoma
B. Syringomyelia
C. Astrocytoma
D. Haemangioblastoma
E. AVM
CHEST
A chest CT is performed on a 10-year-old boy with known underlying chronic lung changes. Current imaging demonstrates laevocardia with areas of air trapping, bronchial dilatation and bronchial wall thickening, which were also present on previous imaging from 1 year earlier. There are no significantly enlarged mediastinal lymph nodes.
Which of the following differential diagnoses would be least likely to account for the underlying changes?
A. Cystic fibrosis
B. IgA deficiency
C. Juvenile dermatomyositis
D. Primary ciliary dyskinesia
E. Recurrent pneumonias
MSK
A 10-year-old boy falls while running for the school bus and hurts his arm. An X-ray demonstrates a fracture through the proximal humeral diaphysis through a ‘bony lesion*. What is the most likely underlying predisposing bone pathology?
A. Giant cell tumour
B. Osteosarcoma
C. Simple bone cyst
D. Eosinophilic granuloma
E. Ewing’s sarcoma
GIT
A 43-year-old woman with known diagnosis of tuberous sclerosis presented to her GP with increasing right upper-abdominal pain. Although the LFT was normal, the GP organised a liver MR in search of angiomyolipomas in the liver. All of the following arc MR features of angiomyolipomas of the liver, except
A. A well-defined mass.
B. Moderately hyperintense signal intensity on T1W images.
C. Moderately hyperintense signal intensity on T2W images.
D. Loss of signal on fat-suppressed sequences.
E. Usually shows late arterial enhancement on the post-contrast sequence.
CHEST
With regard to the progression of pulmonary consolidation on CXR, all of the following options are true except
A. Lung contusion appears in 6 hours and clears in 3-7 days.
B. Aspiration appears in minutes and clears in 24-48 hours unless infected.
C. Lung infarction due to pulmonary embolism manifests after 3-5 days and clears in approximately 3 weeks.
D. Fat embolism appears in 6 hours and clears in 7-10 days.
E. ARDS with difFuse alveolar damage appears after 24-48 hours and clears in 4-6 weeks.
GU
An 88-year-old man with obstructive uropathy and hard nodular prostate gland on digital rectal examination is being further investigated for his prostate cancer. lie has been scheduled for a staging MRI of the prostate. Which one of the following is the characteristic imaging finding of prostate cancer on DWI?
A. High on DWT, low on ADC and corresponding low signal intensity on T2W MRI
B. Low on DWI, high on ADC and corresponding low signal intensity on T2W MRI
C. High on DWI, low on ADC and corresponding high signal intensity on T2W MRI
D. Low on DWI, high on ADC and corresponding high signal intensity on T2W MRI
E. High on DWI, low on ADC and corresponding normal signal intensity on T2W MRI
CHEST
A 50-year-old patient presents with shortness of breath to his GP. Following abnormalities on the chest radiograph, a CT is performed, demonstrating bilateral hilar and right paratracheal lymphadenopathy along with coarse reticulations and nodular thickening along the fissures and bronchovascular bundles. Elevated ACE serum levels are noted.
What is not a typical musculoskeletal manifestation of this disease?
A. Lacy lytic lesions in the phalanges of the hands
B. Polyarthralgia with tenosynovitis
C. Multiple bony lesions with high T2W and intermediate T1W signal characteristics
D. Soft-tissue calcifications
E. Dactylitis
CNS
An infant boy was investigated with MRI for seizures. The left side of the brain is smaller than the right and there is evidence of T2 hypointensity on the gyri. There is diffuse contrast enhancement adjacent to the gyri and sulci on the same side. Some enhancement is also noted along the ipsilateral posterior globe. Which of the following is the most likely diagnosis?
A. Hypoxic ischaemic encephalopathy
B. Meningitis
C. Sturge-Weber syndrome
D. Gliomatosis cerebri
E. Tuberous sclerosis